Results 41 to 50 of about 2,034,857 (344)

The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease. [PDF]

PLoS ONE, 2014
Linear deposition of IgG and complement 3 (C3) along glomerular basement membrane (GBM) is generally revealed in the kidneys of human anti-GBM disease. Our recent studies demonstrated the pathogenic role of complement activation in renal damage of this ...
Rui Ma, Zhao Cui, Shui-Yi Hu, Xiao-Yu Jia, Rui Yang, Xin Zheng, Jie Ao, Gang Liu, Yun-Hua Liao, Ming-Hui Zhao   +9 more
doaj   +1 more source

The outer membrane protease PgtE of Salmonella enterica interferes with the alternative complement pathway by cleaving factors B and H

Frontiers in Microbiology, 2015
The virulence factor PgtE is an outer membrane protease (omptin) of the zoonotic pathogen Salmonella enterica that causes diseases ranging from gastroenteritis to severe enteric fever. It is surface exposed in bacteria that have a short-chain, i.e. rough
Rauna eRiva, Timo K. Korhonen, Seppo eMeri   +2 more
doaj   +1 more source

Borrelia valaisiana resist complement-mediated killing independently of the recruitment of immune regulators and inactivation of complement components. [PDF]

PLoS ONE, 2013
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum.
Jasmin Schwab, Claudia Hammerschmidt, Dania Richter, Christine Skerka, Franz-Rainer Matuschka, Reinhard Wallich, Peter F Zipfel, Peter Kraiczy   +7 more
doaj   +1 more source

Light-Cone Sum Rules for $S$-wave $B\to Kπ$ Form Factors [PDF]

, 2023
We derive a set of light-cone sum rules relating the $S$-wave $B\to K \pi$ hadronic form factors to the $B$-meson light-cone distribution amplitudes (LCDAs), taking into account the complete set of LCDAs up to and including twist four. These results complement the sum rules for the $P$-wave $B\to K \pi$ form factors obtained earlier.
arxiv   +1 more source

Characterization of the sheep Complement Factor B gene (CFB) [PDF]

Veterinary Immunology and Immunopathology, 2011
The Complement Factor B gene (CFB) of the alternative complement pathway has been identified in the sheep Major Histocompatibility Complex (MHC) and its genomic sequence determined. CFB is located approximately 600 bp upstream of the complement C2 gene, contains 18 exons, and manifests the domain signature characteristic of CFB protein. Thirteen single
Qin, J, Munyard, Kylie, Lee, C, Wetherall, John, Groth, David   +4 more
openaire   +3 more sources

Systemic complement activation in age-related macular degeneration. [PDF]

PLoS ONE, 2008
Dysregulation of the alternative pathway (AP) of complement cascade has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of blindness in the elderly. To further test the hypothesis that defective control of
Hendrik P N Scholl, Peter Charbel Issa, Maja Walier, Stefanie Janzer, Beatrix Pollok-Kopp, Florian Börncke, Lars G Fritsche, Ngaihang V Chong, Rolf Fimmers, Thomas Wienker, Frank G Holz, Bernhard H F Weber, Martin Oppermann   +12 more
doaj   +1 more source

Nomenclature for human complement factor B [PDF]

Journal of Immunological Methods, 1993
Abstract In this note is recommended a unified nomenclature for allotypes and variants of human complement factor B, which was approved by the Nomenclature Committee of the International Union of Immunological Societies (IUIS).
openaire   +2 more sources

Complement factor B/C2 in molluscs regulates agglutination and illuminates evolution of the Bf/C2 family

The FASEB Journal, 2019
Complement factor B/C2 family (Bf/C2F) proteins are core complement system components in vertebrates that are absent in invertebrates and have been lost by numerous species, raising evolutionary questions. At least 3 duplication events have occurred from
Maoxiao Peng, Zhi Li, Donghong Niu, Xiaojun Liu, Zhiguo Dong, Jiale Li   +5 more
semanticscholar   +1 more source

Tight Bounds for Complementing Parity Automata [PDF]

Proceedings of MFCS 2014, Springer-Verlag Lecture Notes in Computer Science Vol. 8634(1): pp 499-510, 2014
We follow a connection between tight determinisation and complementation and establish a complementation procedure from parity automata to nondeterministic B\"uchi automata and prove it to be tight up to an $O(n)$ factor, where $n$ is the size of the nondeterministic parity automaton. This factor does not depend on the number of priorities.
arxiv   +1 more source

The principal site of glycation of human complement factor B [PDF]

Biochemical Journal, 1991
Accumulating amino acid sequence data have made it increasingly evident that many essential complement proteins have potentially modifiable lysine residues in putative critical functional regions. Evidence is now presented that glucose is covalently attached to lysine-266 of purified human complement Factor B as a result of glycation.
Marilyn A. Niemann, A S Bhown, E J Miller   +2 more
openaire   +3 more sources