Results 101 to 110 of about 2,642,556 (405)
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Functional Characterization of the Disease-Associated N-Terminal Complement Factor H Mutation W198R
Frontiers in Immunology, 2017 Dysregulation of the complement alternative pathway is involved in the pathogenesis of several diseases, including the kidney diseases atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G).
Marcell Cserhalmi +8 more
doaj +1 more source
Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement [PDF]
, 2004 The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and factor ...
Ajona, D. (Daniel) +8 more
core
Effects of Expression of Streptococcus pneumoniae PspC on the Ability of Streptococcus mitis to Evade Complement-Mediated Immunity [PDF]
, 2021 Streptococcus pneumoniae and Streptococcus mitis are genetically closely related and both frequently colonise the naso-oropharynx, yet S. pneumoniae is a common cause of invasive infections whereas S. mitis is only weakly pathogenic.
Brown, JS +4 more
core
Molecular Oncology, EarlyView.Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran +16 more
wiley +1 more source
On a von Neumann algebra which is a complemented subspace [PDF]
arXiv, 2013 Let M be a von Neumann algebra of type II_1 which is also a complemented subspace of B(H). We establish an algebraic criterion, which ensures that M is an injective von Neumann algebra. As a corollary we show that if M is a complemented factor of type II_1 on a Hilbert space H, then M is injective if its fundamental group is non-trivial.
arxiv
Stealth Immune Properties of Graphene Oxide Enabled by Surface-Bound Complement Factor H.
ACS Nano, 2016 With mounting evidence that nanomaterials can trigger adverse innate immune responses such as complement activation, there is increasing attention to the development of strategies that mask the complement-activating properties of nanomaterials.
Jason N. Belling +8 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Acute Medicine & Surgery, 2021 Aim The complement system is important for defending against pathogens, however, excessive complement activation is associated with a poor prognosis and organ dysfunction in sepsis.
Junji Shimizu +5 more
doaj +1 more source
Classifying complements for groups. Applications [PDF]
Annales de l'institut Fourier, 65 no. 3 (2015), 1349-1365, 2012 Let $A \leq G$ be a subgroup of a group $G$. An $A$-complement of $G$ is a subgroup $H$ of $G$ such that $G = A H$ and $A \cap H = \{1\}$. The \emph{classifying complements problem} asks for the description and classification of all $A$-complements of $G$. We shall give the answer to this problem in three steps. Let $H$ be a given $A$-complement of $G$
arxiv