Results 171 to 180 of about 2,568,825 (335)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Effects of olanzapine on anhedonia in schizophrenia: mediated by complement factor H. [PDF]

Front Psychiatry, 2023
Zhang Y, Tang W, Wang W, Xu F, Lu W, Zhang C.   +5 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Complement Factor H Inhibits CD47‐Mediated Resolution of Inflammation

Immunity, 2017
B. Calippe, S. Augustin, Fanny Béguier, Hugo Charles-Messance, L. Poupel, Jean-Baptiste Conart, S. Hu, S. Lavalette, Alexandre Fauvet, J. Rayes, Olivier Levy, W. Raoul, C. Fitting, Thomas Denèfle, M. Pickering, C. Harris, S. Jorieux, P. Sullivan, J. Sahel, P. Karoyan, P. Sapieha, X. Guillonneau, E. Gautier, F. Sennlaub   +23 more
semanticscholar   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Structural basis for sialic acid-mediated self-recognition by complement factor H.

Nature Chemical Biology, 2015
B. Blaum, J. Hannan, A. Herbert, D. Kavanagh, D. Uhrín, T. Stehle   +5 more
semanticscholar   +1 more source

Complement factor H (CFH) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Complement Factor H Y403H Polymorphism in the Turkish Population

Balkan Journal of Medical Genetics, 2010
Yunus Arikan, Türker Bilgen, Ibrahim Keser   +2 more
doaj   +1 more source