Results 161 to 170 of about 349,286 (299)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study. [PDF]

BJOG, 2023
Lokki AI, Ren Z, Triebwasser M, Daly E, FINNPEC, Perola M, Auro K, Burwick R, Salmon JE, Daly M, Laivuori H, Atkinson JP, Java A, Meri S.   +13 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

The complete amino acid sequence of human complement factor H

, 1988
The complete amino acid sequence of the human complement system regulatory protein, factor H, has been derived from sequencing three overlapping cDNA clones.
Sim, R. B., Day, A. J.; id_orcid, Ripoche, J., Harris, T. J R   +3 more
core   +1 more source

Mutations in UMOD Contribute to the Pathogenesis of ADTKD-UMOD by Influencing the Function of Complement Factor H. [PDF]

J Cell Mol Med
Xie Q, Bai L, Gong K, Hu N, Chen Y.
europepmc   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The Impact of Complement Factor H-Related Protein Gene Deletions on Kidney Transplantation. [PDF]

Scand J Immunol
Markkinen S, Lokki AI, Helanterä I, Ritari J, Partanen J, Meri S, Hyvärinen K.   +6 more
europepmc   +1 more source

Complement factor H attenuates TNF-α-induced inflammation by upregulating EIF3C in rheumatoid arthritis. [PDF]

J Transl Med, 2023
Jia Y, Feng B, Ji X, Tian X, Zhao L, Zhou J, Zhang W, Li M, Fei Y, Wu X.   +9 more
europepmc   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Complement factor H supplementation rather than complete C3 knockout provides therapeutic benefits in IgA nephropathy. [PDF]

Mol Biomed
Li X, Ni X, Yuan X, Wu H, Shi S, Liu L, Lv J, Zhang H, Zhu L.   +8 more
europepmc   +1 more source