Results 161 to 170 of about 16,352,795 (292)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Extended haplotypes at the complement factor H gene locus are associated with liver transplant rejection. [PDF]

Hepatol Commun
Nieuwenhuis LM, Loza BL, Berger SP, Jansen BH, Blokzijl H, Daha MR, Lammerts RGM, Shaked A, Asrani S, Lisman T, Weersma RK, Festen EAM, de Meijer VE, Poppelaars F, TransplantLines Investigators.   +14 more
europepmc   +1 more source

Complement factor H (CFH) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Complement Factor H Mutation-Associated Atypical Haemolytic Uraemic Syndrome Presenting With Dialysis-Dependent Renal Failure: A Case Report. [PDF]

Cureus
Jain A, Mohamed D, Satheesh Nair G, Magriplis M, Yusuf A, Matthews G.   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Immune complex handling in transplantation: central roles for complement factor H, animal models, and translational implications. [PDF]

Front Immunol
Quigg RJ, Alexander JJ.
europepmc   +1 more source

Effects of olanzapine on anhedonia in schizophrenia: mediated by complement factor H. [PDF]

Front Psychiatry, 2023
Zhang Y, Tang W, Wang W, Xu F, Lu W, Zhang C.   +5 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Multi-omics triangulation identifies complement factor H as a genetically supported protective factor in IgA nephropathy. [PDF]

Clin Kidney J
Shao N, Tan K, Chen P, Luo Q.
europepmc   +1 more source