Outer membrane protein OMP76 of Riemerella anatipestifer contributes to complement evasion and virulence by binding to duck complement factor vitronectin [PDF]
Virulence, 2023 Riemerella anatipestifer is an important bacterial pathogen in poultry. Pathogenic bacteria recruit host complement factors to resist the bactericidal effect of serum complement.
Sen Li +11 more
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Complement evasion factor (CEF), a novel immune evasion factor of Streptococcus pyogenes [PDF]
Virulence, 2022 Streptococcus pyogenes, a leading human pathogen, is responsible for a wide range of diseases, including skin and soft tissue infections and severe invasive diseases. S.
Haniyeh Aghababa +5 more
doaj +3 more sources
Complement Evasion in Borrelia spirochetes: Mechanisms and Opportunities for Intervention [PDF]
Antibiotics, 2019 Lyme disease (LD) is an increasingly prevalent, climate change-accelerated, vector-borne infectious disease with significant morbidity and cost in a proportion of patients who experience ongoing symptoms after antibiotic treatment, a condition known as ...
Jonathan W. Locke
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The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis [PDF]
Frontiers in Immunology, 2018 Streptococcus suis is an emerging zoonotic pathogen causing streptococcal toxic shock like syndrome (STSLS), meningitis, septicemia, and even sudden death in human and pigs.
Simin Deng +10 more
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Evasion Mechanisms Used by Pathogens to Escape the Lectin Complement Pathway [PDF]
Frontiers in Microbiology, 2017 The complement system is a crucial defensive network that protects the host against invading pathogens. It is part of the innate immune system and can be initiated via three pathways: the lectin, classical and alternative activation pathway.
Anne Rosbjerg +3 more
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Complement Evasion Strategies of Viruses: An Overview [PDF]
Frontiers in Microbiology, 2017 Being a major first line of immune defense, the complement system keeps a constant vigil against viruses. Its ability to recognize large panoply of viruses and virus-infected cells, and trigger the effector pathways, results in neutralization of viruses ...
Palak Agrawal +4 more
doaj +2 more sources
Candidiasis: Insights into Virulence Factors, Complement Evasion and Antifungal Drug Resistance [PDF]
MicroorganismsInvasive fungal infections constitute a substantial global health burden, with invasive candidiasis representing approximately 70% of reported cases worldwide.
Nidaa Riaz Gaffar +2 more
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Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host [PDF]
Frontiers in Microbiology, 2019 Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
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IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism [PDF]
Virulence, 2018 Streptococcus suis (S. suis) causes meningitis, arthritis and endocarditis in piglets. The aim of this study was to characterize the IgM degrading enzyme of S.
Viktoria Rungelrath +12 more
doaj +2 more sources
Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q [PDF]
Frontiers in ImmunologyHelminths produce calreticulin (CRT) to immunomodulate the host immune system as a survival strategy. However, the structure of helminth-derived CRT and the structural basis of the immune evasion process remains unclarified. Previous study found that the
Zhihui Jia +11 more
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