Results 11 to 20 of about 505,979 (246)
Factor H Family Proteins in Complement Evasion of Microorganisms [PDF]
Frontiers in Immunology, 2017 Human-pathogenic microbes possess various means to avoid destruction by our immune system. These include interactions with the host complement system that may facilitate pathogen entry into cells and tissues, expression of molecules that defuse the ...
Mihály Józsi
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Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q [PDF]
Frontiers in ImmunologyHelminths produce calreticulin (CRT) to immunomodulate the host immune system as a survival strategy. However, the structure of helminth-derived CRT and the structural basis of the immune evasion process remains unclarified. Previous study found that the
Zhihui Jia +11 more
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Human Complement Evasion Is Widespread Among Lyme Borreliosis Spirochete Species [PDF]
PathogensDisseminated human Lyme borreliosis is primarily associated with invasive spirochetes from the Borrelia burgdorferi sensu lato complex. Host–Borrelia interactions have been studied in a diverse range of vertebrate reservoirs.
Maryna Golovchenko +4 more
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The mechanisms of eluding of herpesvirus from complement system
Zdorovʹe Rebenka, 2013 The article presents the basic mechanisms of the complement system, and outlines strategies of evasion of herpesvirus complement-mediated destruction.
Ye.А. Kruger
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Complement Evasion by Lyme Disease Spirochetes [PDF]
Trends in Microbiology, 2020 Jon T Skare, Brandon L Garcia
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Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies. [PDF]
J Innate Immun, 2019 The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for
Laabei M, Ermert D, Ermert D.
europepmc +3 more sources
Microbiology Spectrum, 2023 Plasmodium parasites are the etiological agents of malaria, a disease responsible for over half a million deaths annually. Successful completion of the parasite’s life cycle in the vertebrate host and transmission to a mosquito vector is contingent upon ...
Medard Ernest +7 more
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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Hijacking Factor H for Complement Immune Evasion
Frontiers in Immunology, 2021 The complement system is an essential player in innate and adaptive immunity. It consists of three pathways (alternative, classical, and lectin) that initiate either spontaneously (alternative) or in response to danger (all pathways). Complement leads to
Sara R. Moore +3 more
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Mechanism of Borrelia immune evasion by FhbA-related proteins.
PLoS Pathogens, 2022 Immune evasion facilitates survival of Borrelia, leading to infections like relapsing fever and Lyme disease. Important mechanism for complement evasion is acquisition of the main host complement inhibitor, factor H (FH). By determining the 2.2 Å crystal
Konstantin Kogan +6 more
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