Results 11 to 20 of about 32,418 (239)
Hijacking Complement Regulatory Proteins for Bacterial Immune Evasion
Frontiers in Microbiology, 2016 The human complement system plays an important role in the defense against invading pathogens, inflammation and homeostasis. Invading microbes, such as bacteria, directly activate the complement system resulting in the formation of chemoattractants and ...
Elise Sofie Hovingh +4 more
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Factor H Family Proteins in Complement Evasion of Microorganisms [PDF]
Frontiers in Immunology, 2017 Human-pathogenic microbes possess various means to avoid destruction by our immune system. These include interactions with the host complement system that may facilitate pathogen entry into cells and tissues, expression of molecules that defuse the ...
Mihály Józsi
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Complement Attack against Aspergillus and Corresponding Evasion Mechanisms [PDF]
Interdisciplinary Perspectives on Infectious Diseases, 2012 Invasive aspergillosis shows a high mortality rate particularly in immunocompromised patients. Perpetually increasing numbers of affected patients highlight the importance of a clearer understanding of interactions between innate immunity and fungi ...
Cornelia Speth, Günter Rambach
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Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy [PDF]
Frontiers in Immunology, 2017 As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses by producing a variety of immunomodulatory molecules to escape from host immune attack, but the mechanisms underlying the immune evasion are not well understood ...
Limei Zhao +13 more
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Complement Evasion by Lyme Disease Spirochetes [PDF]
Trends in Microbiology, 2020 Jon T Skare, Brandon L Garcia
exaly +2 more sources
Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies. [PDF]
J Innate Immun, 2019 The human host has evolved elaborate protection mechanisms to prevent infection from the billions of microorganisms to which it host is exposed and is home. One of these systems, complement, is an evolutionary ancient arm of innate immunity essential for
Laabei M, Ermert D, Ermert D.
europepmc +3 more sources
Microbiology Spectrum, 2023 Plasmodium parasites are the etiological agents of malaria, a disease responsible for over half a million deaths annually. Successful completion of the parasite’s life cycle in the vertebrate host and transmission to a mosquito vector is contingent upon ...
Medard Ernest +7 more
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The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System
Biomolecules, 2022 The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi +5 more
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Hijacking Factor H for Complement Immune Evasion
Frontiers in Immunology, 2021 The complement system is an essential player in innate and adaptive immunity. It consists of three pathways (alternative, classical, and lectin) that initiate either spontaneously (alternative) or in response to danger (all pathways). Complement leads to
Sara R. Moore +3 more
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Mechanism of Borrelia immune evasion by FhbA-related proteins.
PLoS Pathogens, 2022 Immune evasion facilitates survival of Borrelia, leading to infections like relapsing fever and Lyme disease. Important mechanism for complement evasion is acquisition of the main host complement inhibitor, factor H (FH). By determining the 2.2 Å crystal
Konstantin Kogan +6 more
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