Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad +6 more
wiley +1 more source
The complement cascade in Alzheimer's disease: modern implications of an ancient immune protagonist. [PDF]
Papavergi MT +3 more
europepmc +1 more source
Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha +14 more
wiley +1 more source
Chronic Glomerular Thrombotic Microangiopathy in a 72-Year-Old Patient with B-Cell Chronic Lymphocytic Leukemia and IgG Lambda Paraprotein. [PDF]
Bitó L +5 more
europepmc +1 more source
Structural water is harnessed as an active co‐monomer to drive supramolecular polymerization in bulk water. Zinc(II) Salphen complexes confine water molecules to form hollow, metal–organic nanofibers that assemble into adaptive hydrogels with thermoresponsive mechanics and selective chiral recognition.
Merlin R. Stühler +10 more
wiley +1 more source
Plasma Proteomic Signatures of Pediatric Sepsis Reveal Persistent Inflammation and Phase-Specific Biomarkers. [PDF]
Alhamdan F +7 more
europepmc +1 more source
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Complement system activation in wild boar (<i>Sus scrofa</i>) following parenteral administration of heat-inactivated <i>Mycobacterium bovis</i>. [PDF]
Villar M +12 more
europepmc +1 more source
Hamster to rat kidney xenotransplantation: effects of FK506, cyclophosphamide, and organ perfusion [PDF]
Demetris, AJ +8 more
core
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley +1 more source

