Complement pathway, classical - Open Access .click

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Alternate and Classical Pathway Components of Complement in the Normal Cornea

Archives of Ophthalmology, 1980
Activation of complement by either the classical or alternate pathway may be involved in corneal inflammation. This study was undertaken to determine whether the normal human cornea contains components for both classical and alternate pathway activation of complement.
B J, Mondino +4 more
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Synthesis of classical pathway complement components by chondrocytes.

Immunology, 1996
Using immunohistochemical studies, C1q, C1s, C4 and C2 were detected in chondrocytes in normal human articular cartilage and macroscopically normal articular cartilage from the inferior surfaces of hip joints of patients with osteoarthritis. Using reverse-transcribed polymerase chain reaction (RT-PCR), mRNA for C1q, C1s, C4 and C2 was also detected in ...
Bradley, K. +6 more
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Monoclonal Antibodies against Components of the Classical Pathway of Complement

Complement and Inflammation, 2017
Activation of the classical pathway of complement involves several binding and enzymatic cleavage processes. Binding and enzymatic activation results in the appearance of new structures in the individual components. This report describes the different activation steps for Clq, Clr, Cls, C4 and C2 and summarizes monoclonal antibodies reported so far ...
H P, Heinz, M, Loos
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CLASSICAL COMPLEMENT PATHWAY IN HIV INFECTION