Results 261 to 270 of about 248,329 (336)

Activation of the Complement/Lectin Pathway, Angiopoietin/Tie-2/VEGF-System, Cytokines and Chemokines in Different Angioedema Subtypes. [PDF]

Eur J Immunol
Duda KM, Gehring M, Wedi B.
europepmc   +1 more source

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Reinforcement Learning Approach to Advance Non‐Fullerene Acceptor‐Based Semi‐Transparent Organic Solar Cell

Advanced Theory and Simulations, EarlyView.
This study introduces a deep Q‐learning framework for semi‐transparent organic solar cells, combining AI and the Transfer Matrix Method to balance transparency/efficiency. Targeting PBDB‐T:ITIC‐based layers with asymmetric DMD contacts, the algorithm optimizes thickness/material properties, achieving 48.97% AVT and sustained photocurrent.
Erman Cokduygulular, Muhammed Yusuf Aykut, Caglar Cetinkaya   +2 more
wiley   +1 more source

Complement Factor B Deficiency Is Dispensable for Female Fertility but Affects Microbiome Diversity and Complement Activity. [PDF]

Int J Mol Sci
Sunamoto M, Morohoshi K, Sato B, Mihashi R, Inui M, Yamada M, Miyado K, Kawano N.   +7 more
europepmc   +1 more source

Exploring Phonon Interference: Insights From a Nano‐Scale Silicon Double Slit Atomistic Simulation

Advanced Theory and Simulations, EarlyView.
Classical Waves at the Atomic Scale: Molecular Dynamics Reveal Phonon Interference in Silicon Nanostructures. Abstract In this study, the classic double‐slit experiment, originally developed for light waves is successfully adapted, to investigate the behavior of phonons in crystalline silicon.
Efstratios Nikidis, Paul Desmarchelier, Yoshiaki Nakamura, Anne Tanguy, Konstantinos Termentzidis, Joseph Kioseoglou   +5 more
wiley   +1 more source

Proteomic Landscape of Colorectal Cancer Derived Liver Metastasis Reveals Three Distinct Phenotypes With Specific Signaling and Enhanced Survival. [PDF]

Mol Cell Proteomics
Nissen P, Popova NV, Gocke A, Smit DJ, Wong GYM, McKay MJ, Hugh TJ, David K, Juhl H, Voß H, Marquardt JU, Nashan B, Schlüter H, Molloy MP, Jücker M.   +14 more
europepmc   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Regulation of the terminal complement cascade in adipose tissue for control of its volume, cellularity, and fibrosis. [PDF]

Obesity (Silver Spring)
Kruglikov IL, Scherer PE.
europepmc   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

Plasma complement proteins as biomarkers and therapeutic targets in chronic kidney disease: a Mendelian randomization analysis. [PDF]

Ren Fail
Xu YP, Song ZQ, Chen ML, Fang YL, Zhang HD.   +4 more
europepmc   +1 more source