Results 61 to 70 of about 247,050 (333)

Classical and alternate complement factor overexpression in non-obese weight matched women with polycystic ovary syndrome does not correlate with vitamin D

open access: yesFrontiers in Endocrinology, 2022
IntroductionWomen with polycystic ovary syndrome (PCOS) exhibit complement factor expression changes that may be obesity-driven rather than an intrinsic facet of PCOS; furthermore, complement changes have been associated with vitamin D deficiency, a ...
Abu Saleh Md Moin   +3 more
doaj   +1 more source

Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review. [PDF]

open access: yes, 2014
Chronic indwelling catheters have been reported to be associated with membranoproliferative glomerulonephritis (MPGN) via the activation of the classical complement pathway in association with bacterial infections such as coagulase negative ...
Nast, Cynthia C   +3 more
core   +2 more sources

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway.

open access: yesBlood, 2018
The mechanisms by which exposure to heparin initiates antibody responses in many, if not most, recipients are poorly understood. We recently demonstrated that antigenic platelet factor 4 (PF4)/heparin complexes activate complement in plasma and bind to B
S. Khandelwal   +12 more
semanticscholar   +1 more source

Characterization of the Classical Complement Pathway of Rainbow Trout [PDF]

open access: yesJournal of the Faculty of Agriculture, Kyushu University, 1988
Characteristics of the classical complement pathway (CCP) of rainbow trout Salmo gairdneti was examined using sheep red blood cells sensitized with porgy Pagrms major antibody which is compatible with rainbow trout complement. The rainbow trout CCP showed the highest activity when the reaction was performed at 20-25°C and around pH 7.5, and the ...
Tomoki Yano, Miki Nakao
openaire   +1 more source

Effect of anticomplement agent K-76 COOH in hamster-to-rat and guinea pig- to-rat xenotransplantation [PDF]

open access: yes, 1995
In normal rats, the xenobiotic K76 inhibited the C5 and probably the C2 and C3 steps of complement and effectively depressed classical complement pathway activity, alternative complement pathway activity, and the C3 complement component during and well ...
Adachi   +41 more
core   +2 more sources

Activation of the classical pathway of complement by rheumatoid factors [PDF]

open access: yesArthritis & Rheumatism, 1982
AbstractA simple, sensitive solid‐phase radioimmunoassay to quantitate the activation of the classical pathway of complement by rheumatoid factor (RF) is described. RF (purified, in serum or synovial fluid) was bound to reduced and alkylated IgG adsorbed to polyvinyl chloride microtiter plates and reacted with diluted normal human serum (complement ...
John G. Curd   +5 more
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

DYSFUNCTION OF COMPLEMENT SYSTEM IN FAMILIAL MEDITERRANEAN FEVER

open access: yesМедицинская иммунология, 2014
. During attacks of familial mediterranean fever (FMF), multiple systemic events are triggered, most of which promote autoinflammatory reactions. A molecular pattern of immune abnormalities in FMF is yet unclear.
G. M. Mkrtchyan   +4 more
doaj   +1 more source

Measuring Total Classical Pathway and Activities of Individual Components of the Mouse Complement Pathway

open access: yesBio-Protocol, 2021
The complement system is a central component of innate immunity, responsible for recognition and killing of bacteria by tagging invaders through opsonisation, thereby promoting phagocytosis, and by direct lysis.
Wioleta Zelek
doaj   +1 more source

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