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Complement Receptors and Cell Associated Complement Components
Immunological Communications, 1977Membrane receptors for activated complement components are widely distributed amongst tissue cells of most mammalian species. Common amongst these are receptors for C3b which mediate many of the biological functions of C3. In addition, the genetic control of certain complement components is linked to the genes which code for the major ...
I, McConnell, P J, Lachmann
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Journal of Immunology, 1986
Receptors for C3 degradation fragments (CR1, CR2, and CR3) are present on many human cells including phagocytes and lymphoid cells and may be critical in the attachment of invading microorganisms. In these studies Candida were found to mimic the human CR
J. Edwards +7 more
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Receptors for C3 degradation fragments (CR1, CR2, and CR3) are present on many human cells including phagocytes and lymphoid cells and may be critical in the attachment of invading microorganisms. In these studies Candida were found to mimic the human CR
J. Edwards +7 more
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Complement receptors and phagocytosis
Current Opinion in Immunology, 1991Current understanding of the molecular mechanisms involved in regulating the phagocytic function of monocytes, macrophages and polymorphonuclear leukocytes is summarized, giving emphasis to the role of the phagocyte integrins of the CD11/CD18 family. New data relating to the hypotheses that optimal function of these receptors is a property of activated
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Revealing the signaling of complement receptors C3aR and C5aR1 by anaphylatoxins
Nature Chemical Biology, 2023Yue Wang +12 more
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Complement Receptors in Neutrophils
Critical Reviews™ in Immunology, 1995Human neutrophils contain numerous intracellular granules and vesicles that are exocytosed in a hierarchic manner on stimulation of the neutrophil with inflammatory mediators. Secretory vesicles are mobilized completely to the plasma membrane when neutrophils are stimulated with inflammatory mediators in nanomolar concentrations. There is evidence that
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Complement receptor structure and function
Immunology Today, 1985Membrane complement receptors (CRs) are now recognized as important cell-bound components of the complement system and research into the structure and function of complement receptors is one of the main thrusts of current complement research.
G D, Ross, J P, Atkinson
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Assays for Membrane Complement Receptors
Current Protocols in Immunology, 1994AbstractLeukocytes express several types of receptors for activated products of the complement (C) system. This unit describes assays for a subset of these receptors: those specific for fixed fragments of C3 (CR1, CR2, CR3, and CR4). Although the assays have been designed for tests of human C receptors, they can often be carried out with rodent (e.g ...
Lynda D, O'Rear, Gordon D, Ross
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Complement Receptors in HIV Infection
Current Molecular Medicine, 2002Similar to other pathogens, HIV can directly activate the complement pathway even in the absence of antibodies. During and after seroconversion, HIV-specific antibodies enhance the activation of complement and increase deposition of complement fragments on virions dramatically.
Susi, Doepper +4 more
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Complement factors and their receptors
Immunopharmacology, 1997In summary, recent advances in molecular cloning of anaphylatoxins and the anaphylatoxin receptors add new dimensions to our investigations and understanding of the molecular mechanisms involved in anaphylatoxin action. Combining knowledge accumulated from peptide modeling of the ligands with mutagenesis studies of these ligands and their receptors ...
J A, Ember, T E, Hugli
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