Results 101 to 110 of about 24,757,633 (403)
Role of the complement system in the tumor microenvironment
Cancer Cell International, 2019 The complement system has traditionally been considered a component of innate immunity against invading pathogens and “nonself” cells. Recent studies have demonstrated the immunoregulatory functions of complement activation in the tumor microenvironment (
Ronghua Zhang +4 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
The role of the complement system in traumatic brain injury: a review
Journal of Neuroinflammation, 2018 Traumatic brain injury (TBI) is an important cause of disability and mortality in the western world. While the initial injury sustained results in damage, it is the subsequent secondary cascade that is thought to be the significant determinant of ...
A. Hammad, L. Westacott, M. Zaben
semanticscholar +1 more source
Frontiers in Immunology, 2018 The complement system is an ancient part of the innate immune system important for both tissue homeostasis and host defense. However, bacteria like Staphylococcus aureus (SA) possess elaborative mechanisms for evading both the complement system and other
Anas H. Abu-Humaidan +5 more
doaj +1 more source
On the Laurent coefficients of the Riemann map for the complement of the Mandelbrot set [PDF]
arXiv, 2014 We straighten a result of [5] about arithmetic properties of the Laurent coefficients of the conformal isomorphism from the complement of the unit disk onto the complement of the Mandelbrot set. This confirms an empirical observation by Don Zagier, see [1]
arxiv
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
On computation of morphism spaces and a direct limit of the bordered Floer homology of knot complements [PDF]
arXiv, 2015 In the bordered Floer theory, gluing thickened torus of positive meridional Dehn twist to the boundary of a knot complement result in the knot complement of increased framing. For a fixed knot K, we construct a direct system of positively framed knot complements and study the direct limit.
arxiv
Computation of transmission eigenvalues by the regularized Schur complement for the boundary integral operators [PDF]
arXiv, 2021 This paper is devoted to the computation of transmission eigenvalues in the inverse acoustic scattering theory. This problem is first reformulated as a two by two boundary system of boundary integral equations. Next, utilizing the Schur complement technique, we develop a Schur complement operator with regularization to obtain a reduced system of ...
arxiv
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Complement system and age-related macular degeneration: drugs and challenges
Drug Design, Development and Therapy, 2019 Age-related macular degeneration (AMD) is directly attributable to vision loss, posing significant pressure on public health. AMD is recognized to be a multi-factorial disease and among them, complement system is under heated discussion in recent years ...
Jiali Wu, Xiaodong Sun
semanticscholar +1 more source