Results 161 to 170 of about 19,068,086 (301)

Complement system-related gene signatures implicated in the recurrence of glioma. [PDF]

Transl Cancer Res
Sun Y, Bao X, Yang Y, Zhang P, Tian N.
europepmc   +1 more source

Components of the alternative pathway

, 1998
Its key role in life preserving functions such as host defense against infections or inflammatory reactions has put the serum complement system at the forefront of biomedical research in both the laboratory and the clinic.
Nilsson Ekdahl, Kristina,, Nilsson, Bo
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The complement system in Alzheimer's disease: mechanisms, biomarkers, and therapeutic implications. [PDF]

Front Immunol
Liu G, Deng B, Han X, Zhao Y, Zeng S, Yu S, Wang L, Wang S, Wu Y, Cai L, Wu Y, Yang H, Chen J.   +12 more
europepmc   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

The complement system in Alzheimer's disease: evaluating biomarker potential in a complex neuroimmune context. [PDF]

J Neuroinflammation
Soni H, Sutherland GT, Hofer MJ.
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

補体学入門 : Cold Activation現象の発見から現在の問題点まで(自然科学系)

, 1997
This short review is for beginners in complementology. The complement system is composed of 30 kinds of physiological proteins: 14 serum complement components; 6 serum inhibitors; 4 membrane inhibitors; and 6 complement receptors on the cellular membrane.
北村, 肇, Kitamura, Hajime
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Complement system in cancer: friend or foe of immunotherapy. [PDF]

J Immunother Cancer
Shah HK, Prem S, Wu X, Liszewski MK, Atkinson JP, Singh AK, Kapoor V.   +6 more
europepmc   +1 more source