Results 151 to 160 of about 1,847,156 (328)

Orally administered β-glucan improves the hemolytic activity of the complement system in horses [PDF]

open access: gold, 2021
Taline Scalco Picetti   +7 more
openalex   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Complement C4, C4A and C4a – What they do and how they differ

open access: yesBrain, Behavior, & Immunity - Health
Meike Heurich   +2 more
doaj   +1 more source

Complement system in cancer: friend or foe of immunotherapy. [PDF]

open access: yesJ Immunother Cancer
Shah HK   +6 more
europepmc   +1 more source

Atypical Hemolytic Uremic Syndrome: Update on the Complement System and What Is New [PDF]

open access: bronze, 2010
Patricia Hirt‐Minkowski   +2 more
openalex   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

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