Results 281 to 290 of about 1,778,418 (315)
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Journal of Burn Care & Rehabilitation, 1981
Although it is still not possible to integrate completely the various components involved in the inflammatory response, we now have the capability of indicating some of the effector pathways and identifying a number of points of interaction between them.
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Although it is still not possible to integrate completely the various components involved in the inflammatory response, we now have the capability of indicating some of the effector pathways and identifying a number of points of interaction between them.
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The complement system and systemic sclerosis
Immunologic Research, 1993Serum concentrations of the various complement components including the classical and the alternative pathways were determined in 58 control healthy subjects and 80 patients with systemic sclerosis (SSC). The mean concentrations of C1q, C2, C5, C6, C7, C9, and factor B were significantly increased in the SSC patients in comparison to controls, while ...
M. Schlesinger +6 more
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1993
Bordet, when working in Pasteur’S laboratory in Paris in 1896, observed that serum of animals immunized with bacteria (Vibrio cholerae), could agglutinate and lyse those bacteria in vitro (either in a test tube or on a slide). If, however, the serum was left at room temperature for one week, or briefly heated at 60 °C, the agglutinating activity ...
M. A. McAleer, Robert B. Sim
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Bordet, when working in Pasteur’S laboratory in Paris in 1896, observed that serum of animals immunized with bacteria (Vibrio cholerae), could agglutinate and lyse those bacteria in vitro (either in a test tube or on a slide). If, however, the serum was left at room temperature for one week, or briefly heated at 60 °C, the agglutinating activity ...
M. A. McAleer, Robert B. Sim
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2018
The complement system consists of a complex cascade of zymogens that leads to the formation of opsonins (predominantly C3b and C4b) that promote phagocytosis and the insertion of the membrane attack complex into the membranes, resulting in lysis. It constitutes one of the first lines of defense against pathogens as it does not require prior maturation ...
José A. Stoute, Sergei Biryukov
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The complement system consists of a complex cascade of zymogens that leads to the formation of opsonins (predominantly C3b and C4b) that promote phagocytosis and the insertion of the membrane attack complex into the membranes, resulting in lysis. It constitutes one of the first lines of defense against pathogens as it does not require prior maturation ...
José A. Stoute, Sergei Biryukov
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1999
Throughout the ages man has been fascinated and at times obsessed by the marvelous, mysterious and even baffling qualities of the blood. In 1889, Hans Buchner described a heat-labile bactericidal principle in the blood which was later identified as the complement system. In 1894, Jules Bordet working at the Pasteur Institute in Metchnikoff’s laboratory
Robert E. Lewis, Julius M. Cruse
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Throughout the ages man has been fascinated and at times obsessed by the marvelous, mysterious and even baffling qualities of the blood. In 1889, Hans Buchner described a heat-labile bactericidal principle in the blood which was later identified as the complement system. In 1894, Jules Bordet working at the Pasteur Institute in Metchnikoff’s laboratory
Robert E. Lewis, Julius M. Cruse
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Proteases of the complement system
Biochemical Society Transactions, 2004The complement system is a group of about 35 soluble and cell-surface proteins which interact to recognize, opsonize and clear or kill invading micro-organisms or altered host cells (e.g. apoptotic or necrotic cells). Complement is a major part of the innate immune system.
Stefanos A. Tsiftsoglou, Robert B. Sim
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The complement system of the duck
Avian Pathology, 1999Antibody (Ab)-dependent and-independent activation of the duck complement (C') system were studied. Ab-independent C' activity exhibited characteristics similar to those of the mammalian alternative C' pathway (ACP), including the selective lysis of rabbit erythrocytes (RRBC), a requirement for Mg2+, but not Ca2+, depletion of activity by zymosan, and ...
Sarah W. S. Chan +2 more
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The Complement System in Uremia
Scandinavian Journal of Urology and Nephrology, 1980Plasma C1q, C1 esterase inactivator, C4, C3 and C3 proactivator were measured in 20 chronic uremic patients on maintenance hemodialysis, in 10 conservatively treated chronic uremic patients and in 20 healthy volunteers. There was no statistical significant difference between the patient groups in any of the measured complement components.
Erik Stoffersen, K. Anker Jørgensen
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Pathways to the Complement System
New England Journal of Medicine, 1972IT has been well appreciated for many years that the serum complement system, through the concerted action of all its components, is a prime mediator of cytotoxic injury to antibody-sensitized cell...
Fred S. Rosen, Irwin H. Lepow
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Evolution of the complement system
Immunology Today, 1991The ancestral form of the alternative pathway of complement activation probably originated as a primitive independent immune system. Subsequent evolution of an adaptive immune response drove the specialization of the classical pathway to connect antibody-mediated nonself recognition to the complement-dependent effector mechanisms.
John P. Atkinson, Timothy C. Farries
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