Results 71 to 80 of about 24,198,541 (380)
Stratified Morse Theory in Arrangements
This paper is a survey of our work based on the stratified Morse theory of Goresky and MacPherson. First we discuss the Morse theory of Euclidean space stratified by an arrangement.
Cohen, Daniel C., Orlik, Peter
core +1 more source
occumb: An R package for site occupancy modeling of eDNA metabarcoding data
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley +1 more source
Inefficient complement system clearance of Trypanosoma cruzi metacyclic trypomastigotes enables resistant strains to invade eukaryotic cells. [PDF]
The complement system is the main arm of the vertebrate innate immune system against pathogen infection. For the protozoan Trypanosoma cruzi, the causative agent of Chagas disease, subverting the complement system and invading the host cells is crucial ...
Igor Cestari, Marcel I Ramirez
doaj +1 more source
Staphylococcus aureus proteins Sbi and Efb recruit human plasmin to degrade complement C3 and C3b [PDF]
Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described.
Barthel, Diana+7 more
core +2 more sources
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
The complement system plays critical roles in development, homeostasis, and regeneration in the central nervous system (CNS) throughout life; however, complement dysregulation in the CNS can lead to damage and disease.
Sarah M Carpanini+2 more
semanticscholar +1 more source
Nonlinear behaviors of first and second order complex digital filters with two’s complement arithmetic [PDF]
For first order complex digital filters with two’s complement arithmetic, it is proved in this paper that overflow does not occur at the steady state if the eigenvalues of the system matrix are inside or on the unit circle. However, if the eigenvalues of
Ho, Charlotte Yuk-Fan+2 more
core +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Nonresonance conditions for arrangements [PDF]
We prove a vanishing theorem for the cohomology of the complement of a complex hyperplane arrangement with coefficients in a complex local system. This result is compared with other vanishing theorems, and used to study Milnor fibers of line arrangements,
Cohen, D., Dimca, A., Orlik, P.
core +3 more sources
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source