Results 71 to 80 of about 24,757,633 (403)
Frontiers in Immunology, 2020 The complement system is an important part of the innate immune system, providing a strong defense against pathogens and removing apoptotic cells and immune complexes.
Esther C. W. de Boer +4 more
doaj +1 more source
Exploring a rheonomic system [PDF]
, 1999 A simple and illustrative rheonomic system is explored in the Lagrangian formalism. The difference between Jacobi's integral and energy is highlighted. A sharp contrast with remarks found in the literature is pointed out.
Antonio S de Castro +6 more
core +2 more sources
International Journal of Immunopathology and Pharmacology, 1992 The human complement system (C) acts to lyse susceptible cells, to promote phagocytosis of target particles, and to solubilize immune-complexes, its activation generates peptides that mediate features of the inflammatory response. It is comprised of a series of plasma zymogens, activated by proteolytic cleavage in a cascade manner, and of plasma and ...
Angelo Agostoni +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Inefficient complement system clearance of Trypanosoma cruzi metacyclic trypomastigotes enables resistant strains to invade eukaryotic cells. [PDF]
PLoS ONE, 2010 The complement system is the main arm of the vertebrate innate immune system against pathogen infection. For the protozoan Trypanosoma cruzi, the causative agent of Chagas disease, subverting the complement system and invading the host cells is crucial ...
Igor Cestari, Marcel I Ramirez
doaj +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Minimax frequency domain performance and robustness optimization of linear feedback systems [PDF]
, 1985 It is shown that feedback system design objectives, such as disturbance attenuation and rejection, power and bandwidth limitation, and robustness, may be expressed in terms of required bounds of the sensitivity function and its complement on the ...
Kwakernaak, Huibert
core +2 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System
Frontiers in Immunology, 2019 The complement system plays critical roles in development, homeostasis, and regeneration in the central nervous system (CNS) throughout life; however, complement dysregulation in the CNS can lead to damage and disease.
Sarah M Carpanini +2 more
semanticscholar +1 more source
Stratified Morse Theory in Arrangements
, 2006 This paper is a survey of our work based on the stratified Morse theory of Goresky and MacPherson. First we discuss the Morse theory of Euclidean space stratified by an arrangement.
Cohen, Daniel C., Orlik, Peter
core +1 more source