Results 71 to 80 of about 2,132,131 (391)

Evidence for the involvement of the Ss protein of the mouse in the hemolytic complement system. [PDF]

The Journal of experimental medicine, 1975
A significant within-strain correlation has been demonstrated between the levels of Ss and hemolytic complement (C) activity in two Ss-high strains. Mouse serum specifically depleted of Ss by absorption with F(ab')2 fragments of anti-Ss had negligible C activity.
Hansen, T H, Shin, H S, Shreffler, D C
openaire   +3 more sources

Evasion Mechanisms Used by Pathogens to Escape the Lectin Complement Pathway

Frontiers in Microbiology, 2017
The complement system is a crucial defensive network that protects the host against invading pathogens. It is part of the innate immune system and can be initiated via three pathways: the lectin, classical and alternative activation pathway.
Anne Rosbjerg, Ninette Genster, Katrine Pilely, Peter Garred   +3 more
doaj   +1 more source

Assessing the relevance of node features for network structure [PDF]

PNAS 106, 11433 (2009), 2008
Networks describe a variety of interacting complex systems in social science, biology and information technology. Usually the nodes of real networks are identified not only by their connections but also by some other characteristics. Examples of characteristics of nodes can be age, gender or nationality of a person in a social network, the abundance of
arxiv   +1 more source

TGF-β Signaling Regulates Neuronal C1q Expression and Developmental Synaptic Refinement [PDF]

, 2014
Immune molecules, including complement proteins C1q and C3, have emerged as critical mediators of synaptic refinement and plasticity. Complement localizes to synapses and refines the developing visual system via C3-dependent microglial phagocytosis of ...
Bialas, Allison R., Stevens, Beth
core   +1 more source

Measuring Total Classical Pathway and Activities of Individual Components of the Mouse Complement Pathway

Bio-Protocol, 2021
The complement system is a central component of innate immunity, responsible for recognition and killing of bacteria by tagging invaders through opsonisation, thereby promoting phagocytosis, and by direct lysis.
Wioleta Zelek
doaj   +1 more source

Therapeutic Inhibition of the Complement System in Diseases of the Central Nervous System

Frontiers in Immunology, 2019
The complement system plays critical roles in development, homeostasis, and regeneration in the central nervous system (CNS) throughout life; however, complement dysregulation in the CNS can lead to damage and disease.
Sarah M Carpanini, Megan Torvell, B. Morgan   +2 more
semanticscholar   +1 more source

Elastohydrodynamics and kinetics of protein patterning in the immunological synapse [PDF]

, 2015
The cellular basis for the adaptive immune response during antigen recognition relies on a specialized protein interface known as the immunological synapse (IS). Understanding the biophysical basis for protein patterning by deciphering the quantitative rules for their formation and motion is an important aspect of characterizing immune cell recognition
arxiv   +1 more source

The role of complement in ocular pathology [PDF]

, 2008
Functionally active complement system and complement regulatory proteins are present in the normal human and rodent eye. Complement activation and its regulation by ocular complement regulatory proteins contribute to the pathology of various ocular ...
A Nicholson-Weller, AE Davis 3rd, AM Blom, AO Edwards, AP Spicer, B Gold, B Li, BE Prosser, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BJ Mondino, BP Morgan, BP Morgan, C Verhagen, D Husain, DM Lublin, DS Bardenstein, DS Bardenstein, DS Gregerson, E Cocuzzi, EF Foxman, FL Ferris, GE Marak, GS Hageman, H Kimura, H Miller, H Takizawa, HJ Muller-Eberhard, I Bykov, J Maller, JH Lass, JH Sohn, JH Sohn, JH Sohn, JJ Alexander, JJ Diehn, JL Haines, JP Atkinson, JP Atkinson, JR Yates, JR Yates, JT Rosenbaum, JY Niederkorn, JZ Nowak, K Funabashi, KBM Reid, LD Hazlett, LV Johnson, LV Johnson, M Krych-Goldberg, M Laine, M Liu, M Nonaka, M Nozaki, MB Powell, MD Willcox, MH Holguin, MJ Watts, MK Liszewski, MK Liszewski, MK Liszewski, MM Frank, MN Mandal, MW Nickells, Nalini S. Bora, NS Bora, NS Bora, NS Bora, NS Bora, NS Bora, P Jha, P Jha, P Jha, PJ Coffey, PS Bora, PS Bora, PS Bora, Puran S. Bora, Purushottam Jha, RA Prendergast, RB Nussenblatt, RF Mullins, RJ Klein, RP Cleveland, RR Caspi, RR Kew, RW Read, S Sivaprasad, SF Wheeler, SJ Ryan, T Miwa, U Pleyer, V Montalvo, Y Bando, YM Qian, YU Kim   +101 more
core   +2 more sources

Complement System and C4d expression in cases of Membranous nephropathy

Brazilian Journal of Nephrology
Introduction: Membranous nephropathy (MN) is one of the major causes of nephrotic syndrome. The complement system plays a key role in the pathophysiology of MN.
Fabiano Bichuette Custódio, Crislaine Aparecida da Silva, Fernanda Rodrigues Helmo, Juliana Reis Machado, Marlene Antônia dos Reis   +4 more
doaj   +1 more source

Integration of a virus membrane protein into the lipid bilayer of target cells as a prerequisite for immune cytolysis [PDF]

, 1979
Structural requirements for membrane antigens on target cells to mediate immune cytolysis were studied in a model system with purified membrane proteins from Semliki Forest virus (SFV). These SFV spike proteins were isolated in the form of detergent- and
Barz, D., Koszinowski, Ulrich H., Morein, B., Schirrmacher, V.   +3 more
core   +1 more source