Complementary-DNA-Strand Cross-Linked Polyacrylamide Hydrogels
We examine networks of complementary-DNA-strand cross-linked polyacrylamide, with and without covalent N,N′-methylene(bis)acrylamide cross-linking, using rheological time–temperature superposition ...
Cong Du, R. Hill
semanticscholar +1 more source
Specificity, flexibility and valence of DNA bonds guide emulsion architecture [PDF]
The specificity and thermal reversibility of DNA interactions have enabled the self-assembly of crystal structures, self-replicating materials and colloidal molecules. Grafting DNA onto liquid interfaces of emulsions leads to exciting new architectural possibilities due to the mobility of the DNA ligands and the patches they form between bound droplets.
arxiv +1 more source
Structural and mutagenic analysis of the RM controller protein C.Esp1396I [PDF]
Bacterial restriction-modification (RM) systems are comprised of two complementary enzymatic activities that prevent the establishment of foreign DNA in a bacterial cell: DNA methylation and DNA restriction.
Kneale, Geoff+2 more
core +5 more sources
Conventionally, in a polymerase chain reaction (PCR), oligonucleotide primers bind to the template DNA in an antiparallel complementary way and the template DNA is amplified as it is.
Vikash Bhardwaj, Kulbhushan Sharma
doaj +1 more source
Efficiency of peptide nucleic acid-directed PCR clamping and its application in the investigation of natural diets of the Japanese eel leptocephali. [PDF]
Polymerase chain reaction (PCR)-clamping using blocking primer and DNA-analogs, such as peptide nucleotide acid (PNA), may be used to selectively amplify target DNA for molecular diet analysis.
Takeshi Terahara+7 more
doaj +1 more source
DNA multi-bit non-volatile memory and bit-shifting operations using addressable electrode arrays and electric field-induced hybridization. [PDF]
DNA has been employed to either store digital information or to perform parallel molecular computing. Relatively unexplored is the ability to combine DNA-based memory and logical operations in a single platform.
Heller, Michael J+3 more
core +3 more sources
Fabrication and functionalization of PCB gold electrodes suitable for DNA-based electrochemical sensing [PDF]
The request of high specificity and selectivity sensors suitable for mass production is a constant demand in medical research. For applications in point-of-care diagnostics and therapy, there is a high demand for low cost and rapid sensing platforms ...
Dhaenens, Kristof+8 more
core +1 more source
Genetic Alterations in Mitochondrial DNA Are Complementary to Nuclear DNA Mutations in Pheochromocytomas [PDF]
Background: Somatic mutations, copy-number variations, and genome instability of mitochondrial DNA (mtDNA) have been reported in different types of cancers and are suggested to play important roles in cancer development and metastasis. However, there is scarce information about pheochromocytomas and paragangliomas (PCCs/PGLs) formation.
Mouna Tabebi+7 more
openaire +3 more sources
Structural basis for CRISPR RNA-guided DNA recognition by Cascade [PDF]
The CRISPR (clustered regularly interspaced short palindromic repeats) immune system in prokaryotes uses small guide RNAs to neutralize invading viruses and plasmids.
A Bolotin+71 more
core +5 more sources
RNA-programmed genome editing in human cells
Type II CRISPR immune systems in bacteria use a dual RNA-guided DNA endonuclease, Cas9, to cleave foreign DNA at specific sites. We show here that Cas9 assembles with hybrid guide RNAs in human cells and can induce the formation of double-strand DNA ...
Martin Jinek+5 more
doaj +1 more source