Results 101 to 110 of about 220,316 (319)

On Schur's complement

open access: yesJournal of Combinatorial Theory, Series A, 1973
AbstractA new proof is given for Haynsworth's formula for Schur's complement.
openaire   +2 more sources

Germline variants in CDKN2A wild‐type melanoma prone families

open access: yesMolecular Oncology, EarlyView.
Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen   +5 more
wiley   +1 more source

Geometric limits of knot complements, II: Graphs determined by their complements [PDF]

open access: yesarXiv, 2009
We prove that there are compact submanifolds of the 3-sphere whose interiors are not homeomorphic to any geometric limit of hyperbolic knot complements.
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

On additive complement of a finite set [PDF]

open access: yesarXiv, 2013
We say the sets of nonnegative integers A and B are additive complements if their sum contains all sufficiently large integers. In this paper we prove a conjecture of Chen and Fang about additive complement of a finite set.
arxiv  

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

A framework for exhaustively mapping functional missense variants

open access: yesMolecular Systems Biology, 2017
Although we now routinely sequence human genomes, we can confidently identify only a fraction of the sequence variants that have a functional impact. Here, we developed a deep mutational scanning framework that produces exhaustive maps for human missense
Jochen Weile   +20 more
doaj   +1 more source

Levels of Reality

open access: yesLanguages, 2019
Two fundamental aspects of conceptual and linguistic structure are examined in relation to one another: organization into strata, each a baseline giving rise to the next by elaboration; and the conceptions of reality implicated at successive levels of ...
Ronald W. Langacker
doaj   +1 more source

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