Results 131 to 140 of about 208,635 (246)

Deficiency of Human Complement Protein C4 Due to Identical Frameshift Mutations in the C4A and C4B Genes [PDF]

, 1999
Marja‐Liisa Lokki, Antonella Circolo, Pirkko Ahokas, Kristi L. Rupert, C. Yung Yu, Harvey R. Colten   +5 more
openalex   +1 more source

GeoFarmer App - A tool to complement extension services and foster active farmers' participation and knowledge exchange [PDF]

, 2020
Anton Eitzinger, Mona Bartling, Christian Feil, Osana Bonilla‐Findji, Nadine Andrieu, Andy Jarvis   +5 more
openalex   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

<i>norCBD</i> disruption affects the H2-type six secretion system and multiple virulence factors in <i>Pseudomonas aeruginosa</i>. [PDF]

Front Microbiol
Haque MM, Badr S, Duan K.
europepmc   +1 more source

Clusterin: modulation of complement function [PDF]

, 1994
Jürg Tschopp, Lars E. French
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Synergistic regulatory mechanisms in glycolysis revealed by pathway transplantation. [PDF]

mBio
Knibbe E, Boonekamp FJ, Stuij R, Savakis P, Pelsma KAJ, Jansen L, Flores C-L, Teusink B, Daran-Lapujade P.   +8 more
europepmc   +1 more source

Analyzing the relationship of Leishmania chagasi and complement resistance through protein-protein interactions, genetic complementation, and innovative techniques

, 2009
Eric J. Scolaro
openalex   +2 more sources

Isolating the Epstein-Barr Virus gp350/220 Binding Site on Complement Receptor Type 2 (CR2/CD21) [PDF]

, 2007
Kendra A. Young, Xiaojiang S. Chen, V. Michael Holers, Jonathan P. Hannan   +3 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source