Results 131 to 140 of about 898,423 (293)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

A Semi-Quantitative Yeast Complementation Platform for Characterizing Urea and Ammonia Transport by Membrane Channels. [PDF]

Curr Protoc
Stoib A, Shojaei S, Siligan C, Horner A.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Predicting epistasis across proteins by structural logic. [PDF]

Proc Natl Acad Sci U S A
Tang M, Cromie GA, Kabir A, Timour MS, Ashmead J, Lo RS, Corley N, DiMaio F, Morizono H, Caldovic L, Ah Mew N, Gropman A, Shehu A, Dudley AM.   +13 more
europepmc   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

<i>REM</i> genes controlling phyllotaxis and yield: bridging findings from <i>Arabidopsis thaliana</i> to <i>Brassica napus</i>. [PDF]

Front Plant Sci
Ferrario CC, Caselli F, Davlatboeva S, Blom EJ, van Tunen A, Gregis V, Kater MM.   +6 more
europepmc   +1 more source

Blastocyst complementation generates exogenic pancreas in vivo in apancreatic cloned pigs

Proceedings of the National Academy of Sciences of the United States of America, 2013
H. Matsunari, H. Nagashima, Masahito Watanabe, K. Umeyama, K. Nakano, Masaki Nagaya, Toshihiro Kobayashi, Tomoyuki Yamaguchi, R. Sumazaki, Leonard A. Herzenberg, H. Nakauchi   +10 more
semanticscholar   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A red/blue optoswitch for temporal control of chloroplast transcription and biogenesis in Arabidopsis. [PDF]

Nat Commun
Uecker F, Ahrens FM, Ruder T, Pfannschmidt T.   +3 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source