Results 231 to 240 of about 208,635 (246)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Development of a Ready-To-Use Bioluminescence Immunosensor for the One-Step Sensitive Detection of Antibodies Against African Swine Fever Virus. [PDF]

Microb Biotechnol
Zhang Z, Li X, Niu Q, Wang J, Liu Y, Afayibo DJA, Chen W, Yang S, Yin H, Guan G, Yang J.   +10 more
europepmc   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Overexpression of AdeIJK RND efflux pump in <i>Acinetobacter baumannii</i> using the mini-Tn<i><b>7</b></i>T-based single copy induction system can lead to <i>lacI^q</i> mutation. [PDF]

Microbiol Spectr
Wimalasekara RL, Patidar R, White D, Kumar A.   +3 more
europepmc   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

The Interaction Network of NSm and Its Role as a Movement Protein in the Tomato Zonate Spot Virus. [PDF]

Viruses
Zhao X, Chen J, Zheng L, Tu J, Wang X, Shi X, Zhang Y, Sun S, Zhang J, Zheng X, Zhang D.   +10 more
europepmc   +1 more source

Complementizer Agreement and the Licensing of DPs: An Account in Terms of Referential Anchoring

Roland Hinterhölzl
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Molecular interplay between peptidoglycan integrity and outer membrane asymmetry in maintaining cell envelope homeostasis. [PDF]

J Bacteriol
Nandy S, Tehrani AF, Hunt-Serracin AC, Biboy J, Pybus C, Vollmer W, Boll JM.   +6 more
europepmc   +1 more source

A critical role of copper homeostasis in the virulence of Klebsiella pneumoniae. [PDF]

Commun Biol
Han M, Chen Q, Xu F, Zhao C, Ma X, Jin Q, Yang J, Wang Y, Qiang R, Hong D, Zhang H.   +10 more
europepmc   +1 more source