Results 71 to 80 of about 208,635 (246)

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs [PDF]

open access: bronze, 2018
Rolf Spirig   +24 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Mitochondrial Heterogeneity

open access: yesFrontiers in Genetics, 2019
Cell-to-cell heterogeneity drives a range of (patho)physiologically important phenomena, such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly of mitochondria, is increasingly being recognized as an important ...
Juvid Aryaman   +6 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Whys and Wherefores: The Aetiology of the Left Periphery (With Reference to Vietnamese)

open access: yesLanguages
This paper offers a detailed description of the left periphery of embedded clauses in Vietnamese. Five kinds of pre-subject constituent are considered in isolation, and in interaction with one another: subordinating conjunctions; embedded topics; fronted
Nigel Duffield
doaj   +1 more source

Innovation at the Grammar-lexis Intersection in World Englishes1

open access: yesNJES: Nordic Journal of English studies, 2019
It has often been claimed that the English complementation system lies at the intersection of grammar and lexis, an area where, in the process of nativization in new varieties of English, innovation and change commonly occur (Olavarría de Ersson and ...
Raquel P. Romasanta
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Amélioration de la valeur alimentaire de la paille de riz par le traitement à l'urée et la complémentation en céréales chez le mouton Peulh sénégalais [PDF]

open access: yesTropicultura, 1997
Improvement of the Nutritive Value of the Rice Straw by Urea Treatment and Cereals Complementation. Four male peulh sheeps were used in series of experimentation. In the first experiment, the sheeps were fed with rice straw without treatment.
Gongnet, GP., Fadiga, S., Cisse, M.
doaj  

Home - About - Disclaimer - Privacy