Results 71 to 80 of about 9,924,949 (260)

Complete response to disitamab vedotin in HER2-low metastatic endometrial carcinoma: a case report and review of the literature

Frontiers in Oncology
Endometrial cancer (EC) is one of the most common gynecologic malignancies with increasing morbidity. The prognosis for patients diagnosed with early-stage EC remains favorable; however, for patients with recurrent or metastatic EC, the prognosis is poor
Hu Feng, Shasha Bi, Shanshan Sun, Hongbo Yang, Haoxing Zhou, Jingjing Mao, Na Li, Fujun Yang   +7 more
doaj   +1 more source

Factors Affecting the Complete Response in Breast and Axillary Regions Following Neoadjuvant Chemotherapy for Breast Cancer [PDF]

Aim: Neoadjuvant chemotherapy (NAC) has transitioned from a treatment modality used solely for inoperable and locally advanced breast cancer to a therapeutic approach for early-stage breast cancer. High-risk patients, such as those with HER2-positive and
Halit Ozgul, Omer Celik, Erhan Aydemir, Azmi Lale, Betul Dagoglu Hark, Remzi Can Cakir, Turan Can Yildiz   +6 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Connecticut State Emergency Response Commission [web site] [Harvested on 2013: Aug. 12]

, 2013
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed June 1, 2011).; At head of title: State of Connecticut.; Official website of the Connecticut State Emergency Response Commission.

core   +1 more source

Relevance of Pathological Complete Response after Neoadjuvant Therapy for Breast Cancer

, 2016
Breast cancer is a heterogeneous disease, and the different biological subtypes have different prognostic impacts. Neoadjuvant trials have recently become popular as they offer several advantages compared to traditional adjuvant trials.
Angela Pennisi, Thomas Kieber-Emmons, Issam Makhoul, Laura Hutchins, Angela Pennisi   +4 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Role of Baseline PET/CT Parameters in Predicting Treatment Response in Patients with Locally Advanced Rectal Cancer Undergoing Total Neoadjuvant Therapy

Medicina
Background and Objectives: Total neoadjuvant therapy (TNT) for locally advanced rectal cancer (LARC) offers significant advantages in terms of pathologic response and long-term survival; however, it is still unclear which patients will benefit the most ...
Ali Kaan Güren, Zilan Başkan, Zeynep Ceren Balaban Genç, Tuğçe Bulun Akyol, Erkam Kocaaslan, Yeşim Ağyol, Pınar Erel, Burak Paçacı, Mustafa Alperen Tunç, Ahmet Demirel, Nargiz Majidova, Nadiye Sever, Abdussamet Çelebi, Selver Işık, Murat Sarı, Osman Köstek, Salih Özgüven, Hilal Alkış, Mustafa Adli, İbrahim Vedat Bayoğlu   +19 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Comparison of efficacy and side effects between short-course radiotherapy and chemotherapy with or without immunotherapy in the neoadjuvant treatment for patients with locally advanced rectal cancer

Frontiers in Oncology
PurposeTo evaluate the efficacy and safety of short-course radiotherapy (SCRT) combined with chemotherapy (ChT) with or without immunotherapy (IT) in the neoadjuvant treatment for patients with locally advanced rectal cancer (LARC).Materials and ...
Shaoqing Niu, Jie Wen, Yangchan Li, Jiayi Yang, Jianqi Xiong, Zhuangzhuang Yang, Chuangqi Chen, Yunying Yang, Yong Bao   +8 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source