Results 91 to 100 of about 5,245,414 (245)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
European Physical Journal C: Particles and Fields, 2019 Critical collapse of a massless scalar field in spherical symmetry is systematically studied. We combine numerical simulations and asymptotic analysis, and synthesize critical collapse, spacetime singularities, and complex science.
Jun-Qi Guo, Hongsheng Zhang
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Abstract and Applied Analysis, 2012 Let denote the operator generated in by , , , and the boundary condition , where , , , and , are complex sequences, , , and is an eigenparameter. In this paper we investigated the principal functions corresponding to the eigenvalues and the spectral ...
Yelda Aygar +2 more
doaj +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
A C 2,α,β estimate for complex Monge–Ampère type equations with conic sigularities
Advanced Nonlinear StudiesIn this paper, we give an alternative approach to the C 2,α,β estimate for complex Monge-Ampère equations with cone singularities along simple normal crossing divisors.
Huang Liding, Tian Gang, Wang Jiaxiang
doaj +1 more source
MathematicsWe studied the movable singularities of solutions of autonomous non-algebraic first-order ordinary differential equations in the form of y′=I(y(t)) and y′=I1(y(t))+I2(y(t))+⋯+In(y(t)), aiming to prove that all movable singularities of all complex ...
Xingyu Liu
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source