Results 81 to 90 of about 5,837 (259)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The blow-up method applied to monodromic singularities
Electronic Journal of Qualitative Theory of Differential EquationsThe blow-up method proves its effectiveness to characterize the integrability of the resonant saddles giving the necessary conditions to have formal integrability and the sufficiency doing the resolution of the associated recurrence differential equation
Brigita Ferčec, Jaume Giné
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Lee–Yang edge singularities in QCD via the Dyson–Schwinger equations
European Physical Journal C: Particles and FieldsWe take the Dyson–Schwinger Equation approach of QCD for the quark propagator at complex chemical potential to study the QCD phase transition. The phase transition line of the $$(2+1)$$ ( 2 + 1 ) -flavor QCD matter in the imaginary chemical potential ...
Zi-Yan Wan, Yi Lu, Fei Gao, Yu-xin Liu
doaj +1 more source
On removable singularities of complex analytic sets [PDF]
Sbornik: Mathematics, 2017 There is proved the sufficiency of several conditions for the removability of singularities of complex-analytic sets in domains of $\mathbb C^n$.
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The Complex Charge Paradigm: A New Approach for Designing Electromagnetic Wavepackets
Advanced Science, 2020 Singularities in optics famously describe a broad range of intriguing phenomena, from vortices and caustics to field divergences near point charges. The diverging fields created by point charges are conventionally seen as a mathematical peculiarity that ...
Liang Jie Wong +2 more
doaj +1 more source
Complex singular wishart matrices and applications
Computers & Mathematics with Applications, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ratnarajah, T., Vaillancourt, R.
openaire +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
, 1971 Numerical solutions to a class of two dimensional harmonic mixed boundary value problems defined on rectangular domains and containing singularities are obtained using conformal transformation methods.
Whiteman, J R, Papamichael, N
core