Results 101 to 110 of about 170,403 (264)
European Physical Journal C: Particles and Fields, 2019 Critical collapse of a massless scalar field in spherical symmetry is systematically studied. We combine numerical simulations and asymptotic analysis, and synthesize critical collapse, spacetime singularities, and complex science.
Jun-Qi Guo, Hongsheng Zhang
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Export of miRNAs from activated macrophages is cooperative and HuR‐dependent
FEBS Letters, EarlyView.This study uncovers a new mechanism for miRNA export regulation in mammalian cells, driven by the RNA‐binding protein HuR. In macrophages, HuR cooperatively binds with miRNAs to export both low‐ and high‐affinity substrates, thereby influencing macrophage activation.
Syamantak Ghosh +2 more
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β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
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Complex Singularity and Unitarity [PDF]
Progress of Theoretical Physics, 1965 Mishima, N., Yamazaki, M.
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
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Abstract and Applied Analysis, 2012 Let denote the operator generated in by , , , and the boundary condition , where , , , and , are complex sequences, , , and is an eigenparameter. In this paper we investigated the principal functions corresponding to the eigenvalues and the spectral ...
Yelda Aygar +2 more
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Non-geometric vacua of the Spin(32)/ℤ 2 heterotic string and little string theories
Journal of High Energy Physics, 2017 We study a class of 6d N $$ \mathcal{N} $$ = (1, 0) non-geometric vacua of the Spin(32)/ℤ 2 heterotic string which can be understood as fibrations of genus-two curves over a complex one-dimensional base.
Anamaría Font, Christoph Mayrhofer
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
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A C 2,α,β estimate for complex Monge–Ampère type equations with conic sigularities
Advanced Nonlinear StudiesIn this paper, we give an alternative approach to the C 2,α,β estimate for complex Monge-Ampère equations with cone singularities along simple normal crossing divisors.
Huang Liding, Tian Gang, Wang Jiaxiang
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
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