Results 121 to 130 of about 5,837 (259)
On singular Calogero-Moser spaces [PDF]
, 2009 Using combinatorial properties of complex reflection groups, we show that the generalised Calogero-Moser space associated to the centre of the corresponding rational Cherednik algebra is singular for all values of its deformation parameter c if and only ...
Bellamy, G.
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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Complex surface singularities from the combinatorial point of view
, 1995 We explore the interplay between graph theory and the topology of isolated singularities of complex surfaces. We study how certain geometric properties of surface singularities are reflected in the dual graphs of their resolutions.
Seade, José, Larrión, Francisco
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A C 2,α,β estimate for complex Monge–Ampère type equations with conic sigularities
Advanced Nonlinear StudiesIn this paper, we give an alternative approach to the C 2,α,β estimate for complex Monge-Ampère equations with cone singularities along simple normal crossing divisors.
Huang Liding, Tian Gang, Wang Jiaxiang
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Abstract and Applied Analysis, 2012 Let denote the operator generated in by , , , and the boundary condition , where , , , and , are complex sequences, , , and is an eigenparameter. In this paper we investigated the principal functions corresponding to the eigenvalues and the spectral ...
Yelda Aygar +2 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
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MathematicsWe studied the movable singularities of solutions of autonomous non-algebraic first-order ordinary differential equations in the form of y′=I(y(t)) and y′=I1(y(t))+I2(y(t))+⋯+In(y(t)), aiming to prove that all movable singularities of all complex ...
Xingyu Liu
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
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Tailoring the energy landscape of a bloch point domain wall with curvature
Nature CommunicationsTopological defects, or singularities, play a key role in the statics and dynamics of complex systems. In magnetism, Bloch point singularities represent point defects that mediate the nucleation of textures such as skyrmions and hopfions.
Sandra Ruiz-Gómez +19 more
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Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
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