Fabrication of 3D photonic band gap crystals for controlling the emission of light [PDF]
EPJ Web of Conferences3D photonic band gap crystals can be used to manipulate light, for example to increase the emission of an emitter. An inverse woodpile photonic band gap crystal has been fabricated in silicon by FIB lithography and reactive ion etching.
Goodwin Melissa J. +6 more
doaj +1 more source
Policy, design and management: the in-vivo laboratory for the science of complex socio-technical systems [PDF]
, 2009 Complex systems scientists cannot by themselves perform experiments on complex socio-technical systems. The best they can do is to perform experiments alongside policy makers who are constantly engaged in experiments as the design and manage the systems ...
Johnson, Jeffrey
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Statistically principled feature selection for single cell transcriptomics
BMC BioinformaticsBackground The high dimensionality of data in single cell transcriptomics (scRNAseq) requires investigators to choose subsets of genes (“feature selection”) for downstream analysis (e.g., unsupervised cell clustering).
Emmanuel P. Dollinger +4 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Response of Complex Systems to Complex Perturbations: the Complexity Matching Effect
, 2006 The dynamical emergence (and subsequent intermittent breakdown) of collective behavior in complex systems is described as a non-Poisson renewal process, characterized by a waiting-time distribution density $\psi (\tau)$ for the time intervals between ...
Allegrini, Paolo +3 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Implementation of pure shift 1H NMR in metabolic phenotyping for structural information recovery of biofluid metabolites with complex spin systems [PDF]
, 2023 José Iván Serrano-Contreras +5 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Unbreakable Relations Between Indonesia-Vietnam Post “Sink the Vessels” Policy: A Complex Systems Approach [PDF]
, 2019 Rusadi Kantaprawira +2 more
openalex +1 more source