Results 61 to 70 of about 3,246,799 (291)
A Note on the Unsteady Cavity Flow in a Tunnel [PDF]
, 1974 The unsteady internal cavitating flow such as the one observed in a pump or a turbine is studied for a simple two-dimensional model of a base-cavitating wedge in an infinite tunnel and it is shown how the cavitation compliance can be calculated using the
Acosta, A. J., Kim, J. H.
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Animals, 2020 Wildlife translocation is an often-used technique to augment populations or remove animals from harm’s way. Unfortunately, many translocation efforts fail to meet their goals for myriad reasons, particularly because translocated animals make large ...
Brett DeGregorio +2 more
doaj +1 more source
, 2009 Inquisitive semantics (cf. Groenendijk, 2008) provides a formal framework for reasoning about information exchange. The central logical notion that the semantics gives rise to is compliance. This paper presents an algorithm that computes the set of compliant responses to a given initiative. The algorithm is sound and complete.
Ciardelli, I.A. +3 more
openaire +3 more sources
Compliance of Healthcare Workers with Hand Hygiene Practices in the Northeast of Iran: an Overt Observation [PDF]
, 2018 Hand hygiene (HH) is one of the most effective methods to prevent transmission and spread of microorganisms from one patient to another, also, it used to reduce the spread of pathogens in clinical settings and to help control outbreaks but compliance is ...
Ghazvini, K. (Kiarash) +2 more
core +3 more sources
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Frontiers in Global Women's HealthIntroductionIn many parts of Asia Pacific (APAC), insufficient intake of micronutrients that are important for conception and pregnancy remains a prevalent issue among women of reproductive age.
Denise Furness +8 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source