Results 41 to 50 of about 3,293,835 (293)

The design of a compliant shape-preserving ring

, 2020
Compliant shape-preserving mechanisms fill a small niche within the established research field of compliant mechanisms. To date no report exists on a compliant shape-preserving ring, even though these mechanisms can give rise to a multitude of practical ...
Radaelli, G. (author), Schreurs, K. W.A. (author), Alijani, F. (author)   +2 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

A Reconfigurable Compliant Four-Bar Mechanism with Multiple Operation Modes

, 2017
International audienceAlthough reconfigurable rigid-body mechanisms have been extensively studied over two decades, their compliant counterparts have not received the similar attention yet.
Abhilash Nayak, Li, Haiyang, Hao, Guangbo, Nayak, Abhilash, Stéphane Caro, Guangbo Hao, Haiyang Li, Caro, Stéphane   +7 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Matching Relationship between Frequency Characteristic and Parasitic Error of Compliant Linear Buffer Mechanism

, 2010
A novel compliant linear buffer mechanism (CLBM) is designed for impact isolation. In view of the incompatible relationship between frequency characteristic and parasitic error of compliant linear mechanism, the mixed compliant linear mechanism(MCLM) is ...
Da Peng Fan, Ya Fei Lu, Lian Chao Zhang, Qing Kun Zhou, Zhi Yong Zhang   +4 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Machine Vision Measurement of Compliant Five Bar Mechanism [PDF]

, 2022
Despite the numerous advantages of compliant and flexi-ble mechanisms, since the flexible members deflect more and it’shard to predict their deformation under complex loading, the dy-namical modeling of mechanisms incorporating compliant linksand ...
Huynh, Andrew
core   +2 more sources

Monolithic scalable compliant mechanisms

PLOS One
Scaling a physical device’s geometry results in mechanical properties changing in various ways (e.g. the cubed-squared law states that for a scaling factor C , mass scales with C 3 and surface area with C
Jared R. Hunter, Bethany Parkinson, Jacob L. Sheffield, Mark B. Rober, Brian D. Jensen, Spencer P. Magleby, Nathan S. Usevitch, Larry L. Howell   +7 more
openaire   +2 more sources

Single piece compliant spatial slider-crank mechanism

, 2014
This paper presents a novel study on the analysis of the "single piece" compliant spatial slider-crank mechanism. In the previous study performed by the authors, a "partially compliant" version of the spatial slider-crank mechanism was introduced.
PARLAKTAŞ, VOLKAN, TANIK, ENGİN
core   +1 more source

Simulation, Analysis, and Experimentation of the Compliant Finger as a Part of Hand-Compliant Mechanism Development

, 2023
Compliant mechanisms are gaining popularity in many different fields, such as in microelectromechanical systems (MEMS), medical applications and health care, opto-mechatronic technology, aerospace engineering, and semiconductor equipment.
Vlastimir Nikolić, Ivan Ćirić, Nenad T. Pavlović, Nikola Ivačko, Maša Milošević, Dušan Stojiljković, Danijela Ristić-Durrant   +6 more
core   +1 more source