Results 71 to 80 of about 3,659,226 (218)

Investigation of soot processes in an optical diesel engine [PDF]

, 2012
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityThis study is dedicated to investigation of soot formed during combustion in diesel engine.
Menkiel, Barbara
core   +3 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Advancing allergy practice in India for respiratory physician

The Journal of Association of Chest Physicians
The landscape of allergy practice in India is undergoing transformative changes, shifting from traditional symptom management to embracing advanced diagnostic and therapeutic modalities for disease modification.
Shambo S. Samajdar, Saibal Moitra
doaj   +1 more source

Component Resolved Testing for Allergic Sensitization

, 2010
Component resolved diagnostics introduces new possibilities regarding diagnosis of allergic diseases and individualized, allergen-specific treatment. Furthermore, refinement of IgE-based testing may help elucidate the correlation or lack of correlation ...
Kirsten Skamstrup Hansen, Lars K. Poulsen, Skamstrup Hansen, Kirsten, Poulsen, Lars K   +3 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Food Allergy Without a Safety Net—Molecular Sensitisation Patterns and Family Quality of Life Among Bulgarian Children in a Setting Without Epinephrine Auto-Injectors

Allergies
Pediatric food allergy is an increasing public health challenge associated with severe allergic reactions, psychosocial burden, and healthcare inequalities.
Polina Kostova, Tsvetelin Lukanov, Tanya Kadiyska, Irena Bogdanova, Dilyana Petkova, Pasha Karaivanova, Sirma Mileva   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Innovative diagnostic techniques and their clinical implications in food allergy: current clinical practice and future perspectives. [PDF]

Front Allergy
Food allergy (FA) is an immune-mediated adverse reaction to food components (mainly proteins) and represents an increasing global health problem, affecting millions of individuals and imposing substantial clinical, psychosocial, and economic burdens ...
Rossi CM, Merli S, Borgonovo L, Giardina M, Yacoub M, Yang B, Losa F, Lodi Rizzini F, Nannipieri S, Piantanida M, Pignatti P, Preziosi D, Rivolta F, Toniato A, Traversi S, Vrenna A, Votto M, Di Sabatino A, Patella V.   +18 more
europepmc   +2 more sources