Results 1 to 10 of about 72,722 (222)

Towards an FDA-cleared basophil activation test [PDF]

Frontiers in Allergy, 2023
Food allergy is a global health problem affecting up to 10% of the world population. Accurate diagnosis of food allergies, however, is still a major challenge in medical offices and for patients seeking alternative avenues of diagnosis.
Oral Alpan, Richard L. Wasserman, Theodore Kim, Amy Darter, Atul Shah, Douglas Jones, Donald McNeil, Henry Li, Laura Ispas, Melinda Rathkopf, Elena Perez, Dareen Siri, Maeve O’Connor, Matthew Plassmeyer, Kimberly Romito, Christina Pettibone, Sean O’Reilly, Søren Ulrik Sønder, Gerald Marti   +18 more
doaj   +4 more sources

Basophil Activation Test as a Biomarker for Taxanes Anaphylaxis [PDF]

Frontiers in Allergy, 2022
IntroductionTaxanes are widely used chemotherapy agents, and their administration, despite premedication, is associated with hypersensitivity reactions (HR) in up to 9% of patients, 1% of which are severe.
Lucila De Campos, Lucila De Campos, Pedro Giavina-Bianchi, Shree Acharya, Donna-Marie Lynch, Jorge Kalil, Mariana C. Castells   +6 more
doaj   +4 more sources

Applications of basophil activation test in paediatric allergic diseases [PDF]

World Allergy Organization Journal
Basophilic granulocytes, containing and releasing histamine after a specific allergy stimulation, are directly involved in IgE-mediated allergic reactions.
Dodi Giulia, MD, Di Filippo Paola, MD, Di Ludovico Armando, MD, Simeone Pasquale, PhD, De Bellis Domenico, MSc, D'ascanio Francesca, MSc, Di Pillo Sabrina, MD, Chiarelli Francesco, PhD, Lanuti Paola, PhD, Attanasi Marina, PhD   +9 more
doaj   +4 more sources

Basophil Activation Test With Aspergillus Molecules: The Case for ABPA [PDF]

Frontiers in Allergy, 2022
BackgroundAllergic bronchopulmonary aspergillosis (ABPA) is an underestimated allergic disease due to Aspergillus fumigatus (AF). The main diagnostic criteria for ABPA rely on the evaluation of immunoglobulin (Ig) E and IgG responses to AF extracts ...
Moïse Michel, Moïse Michel, Youssouf Sereme, Farid Mankouri, Marion Gouitaa, Clarisse Gautier, Jean-Louis Mège, Jean-Louis Mège, Carole Cassagne, Carole Cassagne, Stéphane Ranque, Stéphane Ranque, Martine Reynaud-Gaubert, Martine Reynaud-Gaubert, Joana Vitte, Joana Vitte   +15 more
doaj   +5 more sources

Efficacy predictions for omalizumab treatment based on basophil CD203c expression in patients with allergic rhinitis by basophil activation test -- a real-life, pilot study [PDF]

World Allergy Organization Journal
Background: Basophils are key targets in allergic diseases. Omalizumab blocks IgE binding to FcεRI on basophils, reducing allergic responses. The basophil activation test aids allergy diagnosis, but their role in allergic rhinitis (AR) remains unclear ...
Zhan Zhao, MD, Huidong Chen, MD, Tianyi Liu, MD, Jun Hong, MD, Yuqin Deng, MD, Qingquan Hua, MD   +5 more
doaj   +2 more sources

Basophil activation test and lymphocyte transformation test in cefuroxime-induced anaphylactic reactions [PDF]

Frontiers in Allergy
IntroductionCefuroxime allergy may present as a delayed-type reaction or as an immunoglobulin (Ig)E-mediated immediate-type anaphylactic reaction. The basophil activation test (BAT) is a diagnostic tool for cefuroxime-induced immediate-type reactions ...
Andreas Glässner, Diana Dubrall, Diana Dubrall, Gerda Wurpts, Gerda Wurpts, Philipp Deck, Günther Weindl, Caspar A. Heubach, Amir S. Yazdi, Amir S. Yazdi, Bernhardt Sachs, Bernhardt Sachs   +11 more
doaj   +2 more sources

Prospective study of basophil activation test in suspected perioperative transfusion anaphylaxis [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: Identifying the causative blood product in cases of suspected perioperative transfusion anaphylaxis is challenging because no confirmatory skin tests exist, and few blood-based diagnostic tests are available, potentially resulting in ...
Yasuhiro Amano, MD, PhD, Tasuku Fujii, MD, PhD, Natsumi Kameyama, MHS, Takahiro Tamura, MD, PhD   +3 more
doaj   +2 more sources

Basophil Activation Test in IgE-Mediated Wheat Allergy: Diagnostic and Clinical Applications—A Narrative Review [PDF]

Diagnostics
The basophil activation test (BAT) is an emerging tool in the diagnosis and management of IgE-mediated wheat allergies (WAs), particularly in complex or high-risk phenotypes.
Elena Camelia Berghea, Mădălina Coman-Stanemir, Ioana Raluca Papacocea   +2 more
doaj   +2 more sources

Integrated Diagnostic Approach Using Basophil Activation Test and IgE Assays for Shrimp and Prawn Allergy [PDF]

Medicina
Background and Objectives: Shellfish allergies are common in Vietnam. The basophil activation test (BAT) is a powerful tool in the diagnosis of food allergies.
Nhu N. Q. Nguyen, Thao H. Nguyen, Minh K. Le, Tram B. Duong, Duy L. Pham, Tai T. Tran, Tu H. K. Trinh   +6 more
doaj   +2 more sources

Basophil Activation Test Predicts Cetuximab Anaphylaxis Severity in Alpha-Gal IgE-Positive Patients [PDF]

Diagnostics
Upon first exposure to cetuximab, hypersensitivity reactions can occur. We aimed to assess the utility of the basophil activation test (BAT) to alpha-gal and cetuximab for predicting severe reactions.
Peter Kopač, Ana Koren, Urška Bidovec-Stojkovič, Mitja Košnik, Luka Dejanović, Tanja Mesti, Primož Strojan, Peter Korošec, Janja Ocvirk   +8 more
doaj   +2 more sources