Results 21 to 30 of about 72,722 (222)

Basophil Activation Test for the In Vitro Diagnosis of Tocilizumab Hypersensitivity. [PDF]

Clin Exp Allergy
Summary Basophil activation test (BAT) is a useful approach for diagnosing hypersensitivity reactions to tocilizumab. BAT offers insight into IgE‐allergenic activity beyond sensitisation ...
Koren A, Dejanović L, Korošec P, Kopač P.   +3 more
europepmc   +4 more sources

Basophil activation test: How many basophils are enough? [PDF]

Allergy
Bezinge L, Vogt D, Melone A, Lartigue M, Giegelmann C, Schuster T, Schneider M, Romano M, Gerhold CB, Gerspach MA, Bauer C.   +10 more
europepmc   +3 more sources

Clinical and Translational Significance of Basophils in Patients with Cancer

Cells, 2022
Despite comprising a very small proportion of circulating blood leukocytes, basophils are potent immune effector cells. The high-affinity receptor for IgE (FcɛRI) is expressed on the basophil cell surface and powerful inflammatory mediators such as ...
Jitesh Chauhan, Chara Stavraka, Melanie Grandits, Lais C. G. F. Palhares, Debra H. Josephs, Katie E. Lacy, James Spicer, Heather J. Bax, Sophia N. Karagiannis   +8 more
doaj   +1 more source

Basophil activation tests: time for a reconsideration [PDF]

Expert Review of Clinical Immunology, 2014
Challenges in in vitro allergy diagnostics lie in the development of accessible and reliable assays allowing identification of all offending allergens and cross-reactive structures. Flow-assisted analysis and quantification of in vitro activated basophils serves as a diagnostic instrument with increasing applications developed over the years.
Uyttebroek, Astrid P., Sabato, Vito, Faber, Margaretha A., Cop, Nathalie, Bridts, Chris H., Lapeere, Hilde, De Clerck, Luc S., Ebo, Didier G.   +7 more
openaire   +2 more sources

Diagnostic utility of the basophil activation test in natto-induced hypersensitivity

Allergology International, 2022
Background: Natto (fermented soybeans)-induced hypersensitivity is characterized by delayed symptom onset that hampers diagnosis. We aimed to clarify the clinical utility of the basophil activation test (BAT) in the diagnosis of natto-induced ...
Risa Fukuda, Takeshi Ouchi, Yasuhiko Asahina, Chihiro Shiiya, Sakiko Takeuchi, Fumiyo Yasuda-Sekiguchi, Hisato Iriki, Michiyoshi Kouno, Shinichi Takahashi, Akiko Tanikawa, Masayuki Amagai, Hayato Takahashi   +11 more
doaj   +1 more source

Basophil activation test in Hymenoptera venom allergy. [PDF]

Allergol Select
Before starting venom-specific immunotherapy (VIT), systemic sting reactions to Hymenoptera venoms require allergological workup in order to prove an IgE-mediated reaction and to identify the culprit insect venom. In addition to skin tests and the determination of specific IgE antibodies, the basophil activation test (BAT) using flow cytometry has ...
Eberlein B, Brockow K, Darsow U, Biedermann T, Blank S.   +4 more
europepmc   +4 more sources

Case of a 6-year-old boy with anaphylaxis induced by erythritol with positive skin prick test and negative basophil activation test

Allergy, Asthma & Clinical Immunology, 2022
Erythritol is widely used as an additive in foods and pharmaceuticals. We present the case of a 6-year-old boy who developed an allergy to erythritol. He showed a positive skin prick test result and a negative basophil activation test result.
Satomi Mori, Kazuyuki Kurihara, Chisato Inuo   +2 more
doaj   +1 more source

Using CAST-test to investigate human specific hypersensitivity to the anthrax pathogen

Медицинская иммунология, 2020
We present the results of applying functional cytometric test of antigen-stimulated activation basophils to assess specific immunological reactivity in the people with anthrax, and immunized with anthrax vaccine.
D. G. Ponomarenko, E. L. Rakitina, M. V. Kostyuchenko, O. V. Logvinenko, A. G. Ryazanova, L Yu. Aksenova, N. P. Buravtseva, I. S. Tyumentseva, S. A. Kurcheva, A. N. Kulichenko   +9 more
doaj   +1 more source

Life-threatening rocuronium-induced anaphylactic shock without cutaneous manifestations successfully reversed with sugammadex: a case report

JA Clinical Reports, 2020
Background Recognition of rocuronium-induced anaphylaxis is often challenging, owing to its diverse clinical manifestations. Regarding treatment, several reports have described the efficacy of sugammadex, while conflicting reports have also been ...
Yoshiaki Takise, Jungo Kato, Tomohiro Suhara, Takashige Yamada, Takeru Funakoshi, Hayato Takahashi, Masayuki Amagai, Hiroshi Morisaki   +7 more
doaj   +1 more source

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

Cells, 2020
Basophils are involved in manifestations of hypersensitivity, however, the current understanding of their propensity for activation and their prognostic value in cancer patients remains unclear.
Heather J. Bax, Jitesh Chauhan, Chara Stavraka, Atousa Khiabany, Mano Nakamura, Giulia Pellizzari, Kristina M. Ilieva, Sara Lombardi, Hannah J. Gould, Christopher J. Corrigan, Stephen J. Till, Sidath Katugampola, Paul S. Jones, Claire Barton, Anna Winship, Sharmistha Ghosh, Ana Montes, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis   +19 more
doaj   +1 more source