Basophil Activation in Immediate Drug Hypersensitivity Reactions and Basophil Activation Test (BAT)
In the basophil activation test (BAT), the expression of the degranulation marker lysosomal-associated membrane glycoprotein-3, also termed as CD63, or upregulation of CD203c is determined.
Öner Özdemir
doaj +2 more sources
Allergy to PEG (polyethylene glycol) – sensitivity of basophil activation test with COVID-19 mRNA-vaccine BNT162B2 [PDF]
Basophil activation test (BAT) with COVID-19 mRNA vaccine seems particularly suitable for detecting sensitization to polyethylene glycol (PEG) in patients with PEG allergy.
Bernadette Eberlein +4 more
doaj +2 more sources
Identification of a New and Effective Marker Combination for a Standardized and Automated Bin-Based Basophil Activation Test (BAT) Analysis [PDF]
(1) Background: The basophil activation test (BAT) is a functional whole blood-based ex vivo assay to quantify basophil activation after allergen exposure by flow cytometry.
Johannes Groffmann +8 more
doaj +2 more sources
Basophil activation test to BNT162b2 lacks specificity for predicting allergic reactions to the mRNA vaccine [PDF]
Background: Allergic reactions to the coronavirus 2019 disease (COVID-19) mRNA vaccine (BNT162b2) were originally reported at higher rates than expected, contributing to vaccine hesitancy and, in some cases, unnecessary vaccine avoidance.
Sydney Ann Kee, PhD +8 more
doaj +2 more sources
Basophil activation test in interstitial nephritis. Some comments
[no abstract available]
Salvatore Chirumbolo +2 more
doaj +4 more sources
Multiplex basophil activation tests for allergy diagnosis: present and future applications
The basophil activation test (BAT) has become a major cellular in vitro test for evaluating the allergenic activity of specific IgEs. The impact of the BAT is due to the ability of blood basophil granulocytes to present IgE on the high-affinity FcεRI ...
Peter Korosec, Ana Koren
exaly +3 more sources
Clinical applications of basophil activation test: a review [PDF]
Basophils are one of the most important effector cells involved in IgE-mediated type I hypersensitivity and type 2 inflammation. Basophil activation test (BAT) simulates in vivo type I hyper-sensitivity.
Ya-Dong GAO +2 more
doaj +1 more source
Some food allergic patients who have undergone oral immunotherapy develop exercise-induced allergic reactions on desensitization (EIARDs). This study investigated basophil activation status during the exercise provocation test (EPT) performed to diagnose
Jun Kunizaki +10 more
doaj +1 more source
The prebiotics, galacto-oligosaccharides (GOS), are small carbohydrate molecules with 1–7 galactose units linked to glucose and have been shown to trigger IgE-mediated anaphylaxis in some cases following ingestion.
Li Yuan Gabriella Nadine Lee +13 more
doaj +1 more source
What Basophil Testing Tells Us About CSU Patients – Results of the CORSA Study
Basophil testing is the most effective single approach for diagnosing type-IIb autoimmune chronic spontaneous urticaria (TIIbaiCSU). A positive basophil test has been linked to long disease duration, higher disease activity, a poor response to ...
João Marcelino +17 more
doaj +1 more source

