Results 51 to 60 of about 3,659,226 (218)

Hen’s egg allergy: an update

Бюллетень сибирской медицины, 2018
Hen’s egg allergy is one of the most common problems in pediatrics. This pathology is associated with severe clinical manifestations, often with a risk of anaphylactic reactions.
M. M. Fedotova, O. S. Fedorova, U. V. Konovalova, E. M. Kamaltynova, T. A. Nagaeva, L. M. Ogorodova   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Bayesian analysis suggests independent development of sensitization to different fungal allergens

World Allergy Organization Journal
Background: Fungi are known for their ability to cause allergies, but data on individual sensitization to them are insufficient. The purpose of the study was to carry out a comprehensive analysis of the fungal allergens’ sensitization profile in the ...
Victoria Rodinkova, PhD, Serhii Yuriev, MD, Vitalii Mokin, PhD, Mariia Kryvopustova, PhD, MD, Dmytro Shmundiak, MSc, Mykyta Bortnyk, MSc, Yevhenii Kryzhanovskyi, PhD, Andrii Kurchenko, MD, PhD   +7 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A research agenda for malaria eradication: diagnoses and diagnostics. [PDF]

, 2011
Many of malaria's signs and symptoms are indistinguishable from those of other febrile diseases. Detection of the presence of Plasmodium parasites is essential, therefore, to guide case management.
The maIera Consultative Group on Diagnoses and Diagnostics,, null null, malERA Consultative Group on Diagnoses and Diagnostics   +2 more
core   +1 more source

Investigation into the selection of viewing configurations for three-component planar Doppler velocimetry measurements. [PDF]

, 2007
A method for the calculation of three orthogonal velocity components in planar Doppler velocimetry (PDV) using four or more measured velocity components (to the three typically used) is presented.
Nobes, David S., Charrett, Thomas O. H., Tatam, Ralph P.   +2 more
core   +4 more sources

Advanced gas-path fault diagnostics for stationary gas turbines [PDF]

, 2003
The reliabilities of the gas-path components (compressor, burners and turbines) of a gas turbine (GT) are usually high when compared with those of other GT systems such as fuel supply and control.
Ogaji, Stephen O. T.
core   +4 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source