Results 61 to 70 of about 1,301,914 (340)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Seismic analyses of i-SMR CV supports employing a component mode synthesis technique
Nuclear Engineering and TechnologyTo ensure the safety of next-generation reactors, innovative design concepts and subsequent extensive engineering analyses are essential. However, recurrent modifications of major structures, systems and components require substantial resources for ...
Jun-Yeop Lee +2 more
doaj +1 more source
Integral Field Spectroscopy of the inner kpc of the elliptical galaxy NGC 5044 [PDF]
, 2017 We used Gemini Multi-Object Spectrograph (GMOS) in the Integral Field Unit mode to map the stellar population, emission line flux distributions and gas kinematics in the inner kpc of NGC 5044.
Diniz, Suzi I. F. +6 more
core +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Hybrid Design Optimization Method using Enriched Craig-Bampton Approach [PDF]
, 2009 A hybrid design optimization method is presented which combines a number of techniques such as Component Mode Synthesis (CMS), Design of Computer Experiments and Neural Networks for surrogate modeling with Genetic Algorithms and Sequential Quadratic ...
Akcay Perdahcioglu, D. +2 more
core +1 more source
Transcriptome analyses reveal reduced hepatic lipid synthesis and accumulation in more feed efficient beef cattle [PDF]
, 2018 peer-reviewedThe genetic mechanisms controlling residual feed intake (RFI) in beef cattle are still largely unknown. Here we performed whole transcriptome analyses to identify differentially expressed (DE) genes and their functional roles in liver ...
Fitzsimmons, Carolyn +6 more
core +3 more sources
Thermomechanical Component Mode Synthesis for Blade Casing Interaction Prediction [PDF]
Volume 7B: Structures and Dynamics, 2017 Increasing the efficiency of turbomachines is a major concern as it directly translates into lower environmental impact and improved operational costs. One solution is to reduce the blade-casing operating clearance in order to mitigate aerodynamic losses at the unavoidable cost of increased structural unilateral contact and friction occurrences.
Guérin, Nicolas +4 more
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A synthesis of logic and biology in the design of dependable systems [PDF]
, 2015 The technologies of model-based design and dependability analysis in the design of dependable systems, including software intensive systems, have advanced in recent years.
Papadopoulos, Yiannis
core +1 more source