Results 71 to 80 of about 94,918 (283)
Chemical Engineering Transactions, 2017 Ni-P-PTFE composite film was prepared on the surface of high-speed steel ring, and the preparation process of Ni-P-PTFE composite film was studied in order to improve the wear resistance of mechanical seal ring.
Lianwei Kang
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Effect of TiO2 on electrocatalytic behavior of Ni-Mo alloy coating for hydrogen energy
Materials Science for Energy Technologies, 2018 Ni-Mo-TiO2 composite coating has been developed through electrodeposition method by depositing titanium dioxide (TiO2) nanoparticles parallel to the process of Ni-Mo alloy coating.
Akshatha R. Shetty +1 more
doaj +1 more source
, 2011 The service life of industrial components is limited predominantly by chemical corrosion, mechanical failure or mechanical wear. In the aluminium high pressure die casting industry, liquid aluminium is extremely reactive with the constituents of H13 die ...
Salman, Asma Siddiq
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
electrodeposited ni/al2o3 composite coating on ndfeb permanent magnets
, 2008 NdFeB permanent magnets are highly susceptible to corrosion in various environments. A new composite coating electrodeposited on NdFeB magnets was investigated in this paper.
Song ZL, Song YW, Zhang H
core
In situ formation by laser cladding of a TiC composite coating with a gradient distribution
, 1999 An in situ method was developed to produce an Ni alloy composite coating reinforced by in situ reacted TiC particles with a gradient distribution, using one-step laser cladding with a pre-placed powder mixture on a 5CrMnMo steel substrate.
武晓雷 +1 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source