Results 111 to 120 of about 10,977,169 (397)

Soft material for soft actuators

open access: yesNature Communications, 2017
Inspired by natural muscle, a key challenge in soft robotics is to develop self-contained electrically driven soft actuators with high strain density.
A. Miriyev, K. Stack, Hod Lipson
semanticscholar   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Atomic simulations on the deformation mechanisms in nano-crystalline Ni–Al series Ni-based superalloy based on grain size, strain rate and temperature

open access: yesJournal of Materials Research and Technology, 2023
Molecular Dynamic (MD) simulations were used to investigate the tensile properties of nanocrystalline Ni–Al series Ni-based superalloy at different grain sizes (6.54–20 nm), strain rates (1 × 107–5 × 108 s−1) and temperatures (300–1000 K).
Huicong Dong   +9 more
doaj  

Advanced fiber-composite hybrids--A new structural material [PDF]

open access: yes, 1974
Introduction of metal foil as part of matrix and fiber composite, or ""sandwich'', improves strength and stiffness for multidirectional loading, improves resistance to cyclic loading, and improves impact and erosion resistance of resultant fiber ...
Chamis, C. C.   +2 more
core   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Composite material systems for hydrogen management [PDF]

open access: yes
The task of managing hydrogen entry into elevated temperature structural materials employed in turbomachinery is a critical engineering area for propulsion systems employing hydrogen or decomposable hydrocarbons as fuel. Extant structural materials, such
Pangborn, R. N., Queeney, R. A.
core   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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