Results 141 to 150 of about 10,977,169 (397)

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

Green Composite Materials [PDF]

open access: yesAdvances in Materials Science and Engineering, 2015
Hao Wang   +5 more
openaire   +2 more sources

Rail Corrugation Characteristics Deduced from a Wavelet Analysis of High-Speed Train Interior Noise and Vibration

open access: yesShock and Vibration
A method to deduce the characteristics of rail corrugation was developed and presented in this paper. It has been found that noise and vibration in the train vehicle were primarily contributed by rail corrugation and wheel polygonalisation.
Xiaohan Phrain Gu   +3 more
doaj   +1 more source

Magneto-resistance in three-dimensional composites [PDF]

open access: yes, 2012
In this paper we study the magneto-resistance, i.e. the second-order term of the resistivity perturbed by a low magnetic field, of a three-dimensional composite material.
Briane, Marc, Pater, Laurent
core  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Advanced composite material simulation

open access: yes, 2008
A computational methodology is presented for modeling the non-linear mechanical behavior of composite structures made of FRP (Fiber-Reinforced Polymers) laminates. The model is based on the appropriate combination of the constitutive models of compounding materials, considered to behave as isolated continua, together with additional “closure equations”
Oller Martínez, Sergio Horacio   +3 more
openaire   +4 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

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