Results 141 to 150 of about 11,353,979 (422)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Atomic simulations on the deformation mechanisms in nano-crystalline Ni–Al series Ni-based superalloy based on grain size, strain rate and temperature

open access: yesJournal of Materials Research and Technology, 2023
Molecular Dynamic (MD) simulations were used to investigate the tensile properties of nanocrystalline Ni–Al series Ni-based superalloy at different grain sizes (6.54–20 nm), strain rates (1 × 107–5 × 108 s−1) and temperatures (300–1000 K).
Huicong Dong   +9 more
doaj  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Method of fabricating composite structures [PDF]

open access: yes
A method of fabricating structures formed from composite materials by positioning the structure about a high coefficient of thermal expansion material, wrapping a graphite fiber overwrap about the structure, and thereafter heating the assembly to expand ...
Sigur, W. A.
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Effect of hydrostatic pressure on the anodic dissolution process of X80 steel

open access: yesJournal of Materials Research and Technology
Based on the fact that hydrostatic pressure affects chemical potentials of reaction species and the structure evolution of electric double layer (EDL), the authors propose a generalized-BV equation to analyze the anodic dissolution process of X80 steel ...
Shixiong Wu   +4 more
doaj  

Ultra-high gas barrier and enhanced mechanical properties of corn cellulose nanocomposite films filled with graphene oxide nanosheets

open access: yesCarbohydrate Polymer Technologies and Applications, 2021
A facile and environmentally friendly route has been put forward for fabricating regenerated cellulose-based composite films (RC) with graphene oxide addition (GO).
Dongdong Qin   +6 more
doaj  

Designing high-performance composite joints close to parent materials of aluminum matrix composites [PDF]

open access: yesarXiv, 2017
Composite joints with high-performance close to the parent materials of aluminum matrix composites were fabricated by a new joining technology assisted by ultrasonic vibration. We found both the microstructure and the mechanical performance were systematically dependent on the volume fraction and the distribution of reinforcement particles in the bond ...
arxiv  

Composite material systems for hydrogen management [PDF]

open access: yes
The task of managing hydrogen entry into elevated temperature structural materials employed in turbomachinery is a critical engineering area for propulsion systems employing hydrogen or decomposable hydrocarbons as fuel. Extant structural materials, such
Pangborn, R. N., Queeney, R. A.
core   +1 more source

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