Results 91 to 100 of about 453,515 (291)
Optimization of Composite Material Barrel Based on BP Neural Network Approximate Analysis
MATEC Web of Conferences, 2017 In order to improve the computational efficiency during the simulation and optimization process for the composite structure, the approximate analysis method was studied.
Yadong Xu, Yao Li, Yu Chen
doaj +1 more source
The Extended Regularized Dual Averaging Method for Composite Optimization
, 2021 We present a new algorithm, extended regularized dual averaging (XRDA), for solving composite optimization problems, which are a generalization of the regularized dual averaging (RDA) method. The main novelty of the method is that it allows more flexible
Siegel, Jonathan W., Xu, Jinchao
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Optimization of composite structures [PDF]
Structural optimization is introduced and examples which illustrate potential problems associated with optimized structures are presented. Optimized structures may have very low load carrying ability for an off design condition.
Stroud, W. J.
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Composite laminate tailoring with probabilistic constraints and loads [PDF]
A reliability-based structural synthesis procedure was developed to tailor laminates to meet reliability-based (ply) strength requirements and achieve desirable laminate responses.
Chamis, C. C., Thanedar, P. B.
core +1 more source
Global convergence of splitting methods for nonconvex composite optimization
, 2015 We consider the problem of minimizing the sum of a smooth function $h$ with a bounded Hessian, and a nonsmooth function. We assume that the latter function is a composition of a proper closed function $P$ and a surjective linear map $\cal M$, with the ...
Li, Guoyin, Pong, Ting Kei
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Probabilistic Multilevel Clustering via Composite Transportation Distance
, 2018 We propose a novel probabilistic approach to multilevel clustering problems based on composite transportation distance, which is a variant of transportation distance where the underlying metric is Kullback-Leibler divergence.
Ho, Nhat +3 more
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source