Results 91 to 100 of about 20,421,622 (264)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2000

, 2000
This is a class photograph of the Composite Materials Engineering Graduating Class of 2000 at Winona State University. The students in the photograph are: John Bausano, Jacob Blahnik, Johnny Brody, Jessica Bunker, Nishan Fernando, Ben Fisher, Katie ...
Composite Materials Engineering Department-Winona State University
core  

TCohPrompt: task-coherent prompt-oriented fine-tuning for relation extraction

Complex & Intelligent Systems
Prompt-tuning has emerged as a promising approach for improving the performance of classification tasks by converting them into masked language modeling problems through the insertion of text templates.
Jun Long, Zhuoying Yin, Chao Liu, Wenti Huang   +3 more
doaj   +1 more source

Risk of mental health conditions in bereavement: a population-based analysis of lung cancer spouses

Frontiers in Public Health
BackgroundCaregiving to lung cancer patients is distressing, isolating, and associated with a high burden of anxiety and depression. However, few population-based studies in the U.S. have examined the risk of mental health conditions (MHCs) among spouses
Djin L. Tay, Kline Dubose, Kline Dubose, Jonathan Chipman, Jonathan Chipman, Lee Ellington, Malek Alnajar, Eli Iacob, Caroline Stephens, Katherine A. Ornstein   +9 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2012

, 2012
This is a class photograph of the Composite Materials Engineering Graduating Class of 2012 at Winona State University. The students in the photograph are: Richard Anfinsen, Austin Erdenberger, Ryan Foley, Ben Gerjets, Emily Hammel, Benjamin Malcheski ...
Composite Materials Engineering Department-Winona State University
core  

Non-Abelian Quantum Signal Processing: A Composite Pulse for Fast Analytic Control of Hybrid Oscillator-Qubit Processors

Physical Review X
Quantum signal processing (QSP) transforms a unitary parametrized by a classical variable θ into one governed by a polynomial function f(θ). Though quantum mechanics is linear, such highly nonlinear transformations arise naturally from the curvature of ...
Shraddha Singh, Baptiste Royer, Steven M. Girvin   +2 more
doaj   +1 more source

Vitiligo is associated with an increased risk of cardiovascular diseases: a large-scale, propensity-matched, US-based retrospective studyResearch in context

EBioMedicine
Summary: Background: Vitiligo is an autoimmune disease, characterized by specific destruction of melanocytes. While associations with numerous comorbid conditions, which potentially increase the risk of cardiovascular diseases have been described, data ...
Alicja Frączek, Agnieszka Owczarczyk-Saczonek, Ralf J. Ludwig, Gema Hernandez, Sascha Ständer, Diamant Thaci, Henner Zirpel   +6 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source