Results 181 to 190 of about 2,250,906 (262)

Discovery of Drug-like Inhibitors of the Human Caf1/CNOT7 poly(A)-Selective Nuclease Using Compound Screening. [PDF]

Biomolecules
Kaur I, Hashmi L, Fischer PM, Winkler GS.   +3 more
europepmc   +1 more source

Diabetic RetinaScreen Statistical Bulletin 2020-2021

The data in this report refers to diabetic retinopathy screening in Ireland for the years 2020 and ...
HSE National Screening Service
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Development of the reverse genetics system for viral hemorrhagic septicemia virus genotype IVa and its application in antiviral compound screening. [PDF]

Virol Sin
Huang H, Lu X, Hong T, Chen Y, Yi M, Jia K.   +5 more
europepmc   +1 more source

Diabetic RetinaScreen Statistical Bulletin 2016-2017

The figures in this report relate to people invited by the Diabetic RetinaScreen programme for screening between 01 January 2016 and 31 December ...
HSE National Screening Service
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Matrigel/serum-free, high-fidelity patient-derived tumor-like cell clusters as an in vitro platform for large-scale compound screening and chemoresistance prediction in oral cancer. [PDF]

BMC Med
Luo Y, Li J, Xie S, Yin S, Li J, Zhao J, Sun Y, Qian R, He X, Ge F, Xiao Z, Sui Y, Wang L, Yu H, Lu H, Zhang H, Ye B, Shan X, Cai Z, Xi JJ.   +19 more
europepmc   +1 more source

Chemotropism Assays for Plant Symbiosis and Mycoparasitism Related Compound Screening in Trichoderma atroviride. [PDF]

Front Microbiol, 2020
Moreno-Ruiz D, Lichius A, Turrà D, Di Pietro A, Zeilinger S.   +4 more
europepmc   +1 more source

A deep learning framework for high-throughput mechanism-driven phenotype compound screening and its application to COVID-19 drug repurposing. [PDF]

Nat Mach Intell, 2021
Pham TH, Qiu Y, Zeng J, Xie L, Zhang P.
europepmc   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source