Results 181 to 190 of about 690,492 (301)

Chemotropism Assays for Plant Symbiosis and Mycoparasitism Related Compound Screening in Trichoderma atroviride. [PDF]

Front Microbiol, 2020
Moreno-Ruiz D, Lichius A, Turrà D, Di Pietro A, Zeilinger S.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Correction to "A Structurally Diverse Compound Screening Library to Identify Substrates for Diamine, Polyamine, and Related Acetyltransferases". [PDF]

ACS Omega
Leiva Martel HN, Caro De Silva PL, Painter R, Le VTB, Uychoco P, Figueroa Paniagua D, Endres M, Maltseva N, Joachimiak A, Kuhn ML.   +9 more
europepmc   +1 more source

Screening anti-microbial compounds

Screening anti-microbial ...
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A high throughput strategy for traditional Chinese medicine active compound screening based on Raman spectroscopy. [PDF]

J Pharm Anal
Tian M, Ma X, Li Y, Zang H, Li L.
europepmc   +1 more source

Reduction of chickens use to perform <i>in vitro</i> pre-screening of novel anticoccidials by miniaturisation and increased throughput of the current <i>Eimeria tenella</i> compound-screening model. [PDF]

F1000Res, 2022
Arias-Maroto S, Aguiar-Martins K, Regidor-Cerrillo J, Ortega-Mora L, Marugan-Hernandez V.   +4 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Anti-cancer compound screening identifies Aurora Kinase A inhibition as a means to favor CRISPR/Cas9 gene correction over knock-out. [PDF]

PLoS One
Wilbie D, Eising S, Amo-Addae V, Walther J, Bosman E, Lei Z, de Jong OG, Molenaar JJ, Mastrobattista E.   +8 more
europepmc   +1 more source

Epigenetic Compound Screening Uncovers Small Molecules for Reactivation of Latent HIV-1. [PDF]

Antimicrob Agents Chemother, 2020
Zutz A, Chen L, Sippl F, Humpe A, Schölz C.   +4 more
europepmc   +1 more source