Results 91 to 100 of about 4,214,030 (374)
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou+11 more
wiley +1 more source
Correction: Most Undirected Random Graphs Are Amplifiers of Selection for Birth-Death Dynamics, but Suppressors of Selection for Death-Birth Dynamics. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1004437.].
PLOS Computational Biology Staff
doaj +1 more source
Correction: A quantitative modelling approach for DNA repair on a population scale.
[This corrects the article DOI: 10.1371/journal.pcbi.1010488.].
PLOS Computational Biology Staff
doaj +1 more source
Artificial intelligence (AI) proves to have enormous potential in many areas of healthcare including research and chemical discoveries. Using large amounts of aggregated data, the AI can discover and learn further transforming these data into “usable ...
Nagasundaram Nagarajan+5 more
semanticscholar +1 more source
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Correction: Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1005193.].
PLOS Computational Biology Staff
doaj +1 more source
Metacognition: computation, biology and function [PDF]
Many complex systems maintain a self-referential check and balance. In animals, such reflective monitoring and control processes have been grouped under the rubric of metacognition. In this introductory article to a Theme Issue on metacognition, we review recent and rapidly progressing developments from neuroscience, cognitive psychology, computer ...
Raymond J. Dolan+4 more
openaire +3 more sources
Clinical significance of stratifying prostate cancer patients through specific circulating genes
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian+12 more
wiley +1 more source
Practical Resources for Enhancing the Reproducibility of Mechanistic Modeling in Systems Biology [PDF]
Although reproducibility is a core tenet of the scientific method, it remains challenging to reproduce many results. Surprisingly, this also holds true for computational results in domains such as systems biology where there have been extensive standardization efforts. For example, Tiwari et al.
arxiv
Nano-particle mediated inhibition of Parkinson’s disease using computational biology approach
Parkinson’s disease (PD) arises as neurodegenerative disorder and characterized by progressive deterioration of motor functions due to forfeiture of dopamine-releasing neurons.
A. Kaushik+3 more
semanticscholar +1 more source