Results 101 to 110 of about 4,681,443 (397)

Biotite: a unifying open source computational biology framework in Python

open access: yesBMC Bioinformatics, 2018
As molecular biology is creating an increasing amount of sequence and structure data, the multitude of software to analyze this data is also rising.
Patrick Kunzmann, K. Hamacher
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Reduction of dynamical biochemical reaction networks in computational biology [PDF]

open access: yes, 2012
Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression.
Gorban, Alexander N.   +3 more
core   +6 more sources

Correction: Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug Repurposing. [PDF]

open access: yesPLoS Computational Biology, 2017
[This corrects the article DOI: 10.1371/journal.pcbi.1005135.].
PLOS Computational Biology Staff
doaj   +1 more source

Limits of computational biology

open access: yesIn Silico Biology, 2015
Are we close to a complete inventory of living processes so that we might expect in the near future to reproduce every essential aspect necessary for life? Or are there mechanisms and processes in cells and organisms that are presently inaccessible to us?
openaire   +4 more sources

To Embed or Not: Network Embedding as a Paradigm in Computational Biology

open access: yesFrontiers in Genetics, 2019
Current technology is producing high throughput biomedical data at an ever-growing rate. A common approach to interpreting such data is through network-based analyses. Since biological networks are notoriously complex and hard to decipher, a growing body
W. Nelson   +5 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Correction: Sequential inference as a mode of cognition and its correlates in fronto-parietal and hippocampal brain regions. [PDF]

open access: yesPLoS Computational Biology, 2017
[This corrects the article DOI: 10.1371/journal.pcbi.1005418.].
PLOS Computational Biology Staff
doaj   +1 more source

Application of Computational Biology and Artificial Intelligence Technologies in Cancer Precision Drug Discovery

open access: yesBioMed Research International, 2019
Artificial intelligence (AI) proves to have enormous potential in many areas of healthcare including research and chemical discoveries. Using large amounts of aggregated data, the AI can discover and learn further transforming these data into “usable ...
Nagasundaram Nagarajan   +5 more
semanticscholar   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

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