Results 111 to 120 of about 933,309 (343)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Computational Molecular Biology

open access: yes, 1996
Computational Biology is a fairly new subject that arose in response to the computational problems posed by the analysis and the processing of biomolecular sequence and structure data.
Lenhof, H., Mutzel, P., Vingron, M.
core  

Understanding Genomic Evolution of Olfactory Receptors through Fractal and Mathematical Morphology [PDF]

open access: yes, 2011
Fractals and Mathematical Morphology are immensely used to study many problems in different branches of science and technology including the domain of Biology. There are many more unrevealed facts and figures of genes and genome in Computational Biology.
Arunava Goswami   +5 more
core   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

Computational Biology in Argentina

open access: yesPLoS Computational Biology, 2007
علم الأحياء الحسابي هو علم متعدد التخصصات نشأ من مجالات متباينة مثل الرياضيات والكيمياء والإحصاء والفيزياء وعلم الأحياء وعلوم الكمبيوتر. على الرغم من أن التعريف الدقيق لعلم الأحياء الحسابي بعيد كل البعد عن أن يكون دقيقًا ولا لبس فيه، إلا أن الحقيقة هي أن مئات العلماء في جميع أنحاء العالم يستخدمون بشكل متزايد المهارات من المجالات المذكورة أعلاه للتعامل ...
Sebastián Bassi   +2 more
openaire   +5 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Dynamic Programming for Optimal Control of Set-Up Scheduling with Neural Network Modifications [PDF]

open access: yes, 1992
This paper demonstrates an optimal control solution to change of machine set-up scheduling based on dynamic programming average cost per stage value iteration as set forth by Cararnanis et. al. [2] for the 2D case.
Bradski, Gary
core   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

open access: yesFEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy