Results 121 to 130 of about 4,681,443 (397)
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1003173.].
PLOS Computational Biology Staff
doaj +1 more source
Correction: The role of the encapsulated cargo in microcompartment assembly. [PDF]
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1006351.].
PLOS Computational Biology Staff
doaj +1 more source
The computational stance in biology [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2019 The goal of this article is to call attention to, and to express caution about, the extensive use of computation as an explanatory concept in contemporary biology. Inspired by Dennett's ‘intentional stance’ in the philosophy of mind, I suggest that a ‘computational stance’ can be a productive approach to evaluating the value of computational concepts ...
openaire +3 more sources
Molecular Oncology, EarlyView.In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen +17 more
wiley +1 more source
Development and validation of computational models of cellular interaction [PDF]
, 2004 In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L. +2 more
core +1 more source
Biological Computing Fundamentals and Futures [PDF]
arXiv, 2009 The fields of computing and biology have begun to cross paths in new ways. In this paper a review of the current research in biological computing is presented. Fundamental concepts are introduced and these foundational elements are explored to discuss the possibilities of a new computing paradigm.
arxiv
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1006378.].
PLOS Computational Biology Staff
doaj +1 more source
Putting benchmarks in their rightful place: The heart of computational biology
PLoS Comput. Biol., 2018 Research in computational biology has given rise to a vast number of methods developed to solve scientific problems. For areas in which many approaches exist, researchers have a hard time deciding which tool to select to address a scientific challenge ...
B. Peters +4 more
semanticscholar +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
Molecular Oncology, EarlyView.We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas +15 more
wiley +1 more source
Using Glowscript to Teach Numerical Modeling in Undergraduate Biology Education [PDF]
arXiv, 2022 Mathematical and numerical modeling is an increasingly important, yet often neglected, topic for biology students. We have found Glowscript to facilitate teaching and introducing computer simulations to students. In particular, the built-in the graphics and graphing capabilities can provide students with immediate feedback.
arxiv