Recent Advances of Deep Learning in Bioinformatics and Computational Biology
Frontiers in Genetics, 2019 Extracting inherent valuable knowledge from omics big data remains as a daunting problem in bioinformatics and computational biology. Deep learning, as an emerging branch from machine learning, has exhibited unprecedented performance in quite a few ...
Binhua Tang +3 more
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Correction: Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria. [PDF]
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1005593.].
PLOS Computational Biology Staff
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Deep learning for computational biology
Molecular Systems Biology, 2016 Technological advances in genomics and imaging have led to an explosion of molecular and cellular profiling data from large numbers of samples. This rapid increase in biological data dimension and acquisition rate is challenging conventional analysis ...
Christof Angermueller +3 more
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Correction: Ten Simple Rules for Taking Advantage of Git and GitHub. [PDF]
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1004947.].
PLOS Computational Biology Staff
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A practical guide to methods controlling false discoveries in computational biology
Genome Biology, 2018 In high-throughput studies, hundreds to millions of hypotheses are typically tested. Statistical methods that control the false discovery rate (FDR) have emerged as popular and powerful tools for error rate control.
Keegan Korthauer +8 more
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Improving reproducibility in computational biology research
PLoS Comput. Biol., 2020 1 Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America, 2 Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, 3 Department of ...
J. Papin +4 more
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The prospects of quantum computing in computational molecular biology [PDF]
WIREs Computational Molecular Science, 2020 Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all scientific disciplines. In
C. Outeiral +5 more
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Correction: Dose-response relationships for environmentally mediated infectious disease transmission models. [PDF]
PLoS Computational Biology, 2017 [This corrects the article DOI: 10.1371/journal.pcbi.1005481.].
PLOS Computational Biology Staff
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FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Correction: Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling. [PDF]
PLoS Computational Biology, 2016 [This corrects the article DOI: 10.1371/journal.pcbi.1003877.].
PLOS Computational Biology Staff
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