Developing an NLP-based Recommender System for the Ethical, Legal, and Social Implications of Synthetic Biology [PDF]
Synthetic biology is an emerging field that involves the engineering and re-design of organisms for purposes such as food security, health, and environmental protection. As such, it poses numerous ethical, legal, and social implications (ELSI) for researchers and policy makers.
arxiv
Correction: Dose-response relationships for environmentally mediated infectious disease transmission models. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1005481.].
PLOS Computational Biology Staff
doaj +1 more source
A New Mixed Fractional Derivative with Applications in Computational Biology
This study develops a new definition of a fractional derivative that mixes the definitions of fractional derivatives with singular and non-singular kernels.
K. Hattaf
semanticscholar +1 more source
The prospects of quantum computing in computational molecular biology [PDF]
Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all scientific disciplines. In
C. Outeiral+5 more
semanticscholar +1 more source
Ten Simple Rules When Considering Retirement [PDF]
This is an article submitted to the Ten Simple Rules series of professional development articles published by PLOS Computational Biology.
arxiv +1 more source
Correction: Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1003877.].
PLOS Computational Biology Staff
doaj +1 more source
Multiple sclerosis clinical decision support system based on projection to reference datasets
Abstract Objective Multiple sclerosis (MS) is a multifactorial disease with increasingly complicated management. Our objective is to use on‐demand computational power to address the challenges of dynamically managing MS. Methods A phase 3 clinical trial data (NCT00906399) were used to contextualize the medication efficacy of peg‐interferon beta‐1a vs ...
Chadia Ed‐driouch+13 more
wiley +1 more source
An Optimal Likelihood Free Method for Biological Model Selection [PDF]
Systems biology seeks to create math models of biological systems to reduce inherent biological complexity and provide predictions for applications such as therapeutic development. However, it remains a challenge to determine which math model is correct and how to arrive optimally at the answer.
arxiv
Correction: Measuring Fisher Information Accurately in Correlated Neural Populations. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1004218.].
PLOS Computational Biology Staff
doaj +1 more source
A framework for philosophical biology [PDF]
Advances in biology have mostly relied on theories that were subsequently revised, expanded or eventually refuted using experimental and other means. Theoretical biology used to primarily provide a basis to rationally examine the frameworks within which biological experiments were carried out and to shed light on overlooked gaps in understanding. Today,
arxiv +1 more source