Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Correction: Measuring Fisher Information Accurately in Correlated Neural Populations. [PDF]
PLoS Computational Biology, 2016 [This corrects the article DOI: 10.1371/journal.pcbi.1004218.].
PLOS Computational Biology Staff
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Correction: Sequential inference as a mode of cognition and its correlates in fronto-parietal and hippocampal brain regions. [PDF]
PLoS Computational Biology, 2017 [This corrects the article DOI: 10.1371/journal.pcbi.1005418.].
PLOS Computational Biology Staff
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Correction: lumpGEM: Systematic generation of subnetworks and elementally balanced lumped reactions for the biosynthesis of target metabolites. [PDF]
PLoS Computational Biology, 2017 [This corrects the article DOI: 10.1371/journal.pcbi.1005513.].
PLOS Computational Biology Staff
doaj +1 more source
To Embed or Not: Network Embedding as a Paradigm in Computational Biology
Frontiers in Genetics, 2019 Current technology is producing high throughput biomedical data at an ever-growing rate. A common approach to interpreting such data is through network-based analyses. Since biological networks are notoriously complex and hard to decipher, a growing body
W. Nelson +5 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Erratum: Notification of Republication: Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy. [PDF]
PLoS Computational Biology, 2019 [This corrects the article DOI: 10.1371/journal.pcbi.1006775.].
PLOS Computational Biology Staff
doaj +1 more source
BioMed Research International, 2019 Artificial intelligence (AI) proves to have enormous potential in many areas of healthcare including research and chemical discoveries. Using large amounts of aggregated data, the AI can discover and learn further transforming these data into “usable ...
Nagasundaram Nagarajan +5 more
semanticscholar +1 more source