Results 81 to 90 of about 950,074 (346)

The computational stance in biology [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2019
The goal of this article is to call attention to, and to express caution about, the extensive use of computation as an explanatory concept in contemporary biology. Inspired by Dennett's ‘intentional stance’ in the philosophy of mind, I suggest that a ‘computational stance’ can be a productive approach to evaluating the value of computational concepts ...
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Erratum: Notice of Republication: Simulating Cortical Development as a Self Constructing Process: A Novel Multi-Scale Approach Combining Molecular and Physical Aspects.

PLoS Computational Biology, 2019
[This corrects the article DOI: 10.1371/journal.pcbi.1003173.].
PLOS Computational Biology Staff
doaj   +1 more source

Systems biology in animal sciences [PDF]

, 2011
Systems biology is a rapidly expanding field of research and is applied in a number of biological disciplines. In animal sciences, omics approaches are increasingly used, yielding vast amounts of data, but systems biology approaches to extract ...
Bannink, A., Pas, M.F.W., te, Smits, M.A., Veerkamp, R.F., Woelders, H.   +4 more
core   +3 more sources

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Correction: clusterExperiment and RSEC: A Bioconductor package and framework for clustering of single-cell and other large gene expression datasets.

PLoS Computational Biology, 2019
[This corrects the article DOI: 10.1371/journal.pcbi.1006378.].
PLOS Computational Biology Staff
doaj   +1 more source

An approach to evolving cell signaling networks in silico [PDF]

, 2006
Cell Signaling Networks(CSN) are complex bio-chemical networks which, through evolution, have become highly efficient for governing critical control processes such as immunological responses, cell cycle control or homeostasis.
Decraene, James, Kelly, Ciarán, McMullin, Barry, Mitchell, George G.   +3 more
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Correction: A model for the origin and development of visual orientation selectivity.

PLoS Computational Biology, 2019
[This corrects the article DOI: 10.1371/journal.pcbi.1007254.].
PLOS Computational Biology Staff
doaj   +1 more source

Correction: Most Undirected Random Graphs Are Amplifiers of Selection for Birth-Death Dynamics, but Suppressors of Selection for Death-Birth Dynamics. [PDF]

PLoS Computational Biology, 2019
[This corrects the article DOI: 10.1371/journal.pcbi.1004437.].
PLOS Computational Biology Staff
doaj   +1 more source