Results 71 to 80 of about 2,977,079 (288)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Computational methods for Bayesian model choice

, 2009
In this note, we shortly survey some recent approaches on the approximation of the Bayes factor used in Bayesian hypothesis testing and in Bayesian model choice.
C. P. Robert, Chun-Yong Chan, D. Wraith, Paul M. Goggans   +3 more
core   +4 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Advanced architectural descriptors in foams: novel 3D computational methods [PDF]

, 2013
This work presents 3D computational strategies aimed at providing foam de-structuration of the basic components of a cellular material (struts and cell walls) offering the possibility of analysing separately the structural elements that play an important
Brabant, Loes, Pado-Alonso, Samuel, Rodríguez-Pérez, MA, Solórzano, Eusebio, Van Hoorebeke, Luc, Vicente, J   +5 more
core  

Solving systems of phaseless equations via Kaczmarz methods: A proof of concept study [PDF]

, 2015
We study the Kaczmarz methods for solving systems of quadratic equations, i.e., the generalized phase retrieval problem. The methods extend the Kaczmarz methods for solving systems of linear equations by integrating a phase selection heuristic in each ...
Wei, Ke
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

The computational complexity of traditional Lattice-Boltzmann methods for incompressible fluids

, 2008
It is well-known that in fluid dynamics an alternative to customary direct solution methods (based on the discretization of the fluid fields) is provided by so-called \emph{particle simulation methods}.
Enrico Fonda, Marco Tessarotto, Massimo Tessarotto, Takashi Abe   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Improving CO₂ Capture Efficiency Through Novel CLOU-Based Fuel Reactor Configuration in Chemical Looping Combustion

Energies
Climate change and global decarbonization targets drive the search for more efficient and cost-effective combustion technologies. Chemical looping combustion (CLC) using solid oxygen carriers with chemical looping with oxygen uncoupling (CLOU ...
Anna Zylka, Jaroslaw Krzywanski, Tomasz Czakiert, Marcin Sosnowski, Karolina Grabowska, Dorian Skrobek, Lukasz Lasek   +6 more
doaj   +1 more source

Characterization and frequency analysis of flooding solid flow in semi-arid zone: case of Mekerra catchment in the north-west of Algeria

Applied Water Science, 2020
In this study, we evaluate the soil erosion and solid transport in the oued Mekerra watershed in north-west Algeria. The study area is subject to a semi-arid climate characterized by irregular rainfall and showers, which are often accompanied by ...
M. Diaf, A. Hazzab, A. Yahiaoui, A. Belkendil   +3 more
doaj   +1 more source