Results 51 to 60 of about 1,165,644 (258)

A flexible and scalable scheme for mixing computed formation energies from different levels of theory

npj Computational Materials, 2022
Computational materials discovery efforts are enabled by large databases of properties derived from high-throughput density functional theory (DFT), which now contain millions of calculations at the generalized gradient approximation (GGA) level of ...
Ryan S. Kingsbury, Andrew S. Rosen, Ayush S. Gupta, Jason M. Munro, Shyue Ping Ong, Anubhav Jain, Shyam Dwaraknath, Matthew K. Horton, Kristin A. Persson   +8 more
doaj   +1 more source

Graph theory methods for fog computing: A pseudo-random task graph model for evaluating mobile cloud, fog and edge computing systems

Journal of Edge Computing, 2022
The development and efficient application of Fog Computing technologies necessitate complex tasks associated with the management and processing of large data sets, including the creation of low-level networks that guarantee the functioning of end ...
Andriy V. Ryabko, Oksana V. Zaika, Roman P. Kukharchuk, Tetiana A. Vakaliuk   +3 more
doaj   +1 more source

Theory formation by abduction : a case study based on the chemical revolution [PDF]

, 1990
Abduction is the process of constructing explanations. This chapter suggests that automated abduction is a key to advancing beyond the "routine theory revision" methods developed in early AI research towards automated reasoning systems capable of "world ...
Morris, Steven, O'Rorke, Paul, Schulenburg, David   +2 more
core  

O(N) methods in electronic structure calculations

, 2011
Linear scaling methods, or O(N) methods, have computational and memory requirements which scale linearly with the number of atoms in the system, N, in contrast to standard approaches which scale with the cube of the number of atoms.
, , , , , Alfè D, Ballentine L E, Baroni S, Baroni S, Benzi M, Bernholc J, Bernstein N, Biel B, Bock N Challacombe M Gan C K Henkelman G Nemeth K Niklasson A M N Odell A Schwegler E Tymczak C J Weber V, Bowler D R, Bowler D R, Bowler D R, Bowler D R, Brázdová V, Burger S K, Cankurtaran B O, Challacombe M, Challacombe M Bock N, Chen M, D R Bowler, Ercolessi F, Fattebert J L, Fujiwara T, Goringe C M, Gygi F, Haynes P D, Hine N D M, Horsfield A P, Hoshi T, Hoshi T, Hung L, Hung L Carter E A, Jedrzejewski J, Kramer B, Lanczos C, Monserrat B, Mortensen J J, Otsuka T, Otsuka T Miyazaki T Bowler D R Gillan M J, Pask J E, Pearson M, Press W H, Qiu S Y, Resta R, Rudberg E, Skylaris C K, Skylaris C K, Soler J M, Sánchez-Portal D, T Miyazaki, Torralba A S, Tsuchida E, Watson S, White C A, Yao Y, Zeller R, Zhao Z, Zonias N   +62 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Integrability of a Family of Four-Dimensional Quadratic Lotka–Volterra Complex Systems

Axioms
This work addresses the integrability of four-dimensional quadratic Lotka–Volterra systems exhibiting (1:−1:i:−i) resonance by identifying the parameter constraints required for such properties to exist.
Ivan Mastev, Valery G. Romanovski
doaj   +1 more source

Lattice methods and the nuclear few- and many-body problem

, 2016
We begin with a brief overview of lattice calculations using chiral effective field theory and some recent applications. We then describe several methods for computing scattering on the lattice. After that we focus on the main goal, explaining the theory
A. Ekström, B. Borasoy, B. Borasoy, B. Borasoy, B. Borasoy, B.N. Lu, D. Lee, D. Lee, D. Lee, D.H. Weingarten, E. Epelbaum, E. Epelbaum, E. Epelbaum, E. Epelbaum, E. Epelbaum, G. Hagen, G. Rupak, G. Wlazłowski, H.M. Müller, J. Carlson, J. Carlson, J. Hubbard, J.E. Drut, M. Creutz, M. Creutz, M. Lüscher, M. Lüscher, M. Pine, R.L. Stratonovich, R.T. Scalettar, S. Duane, S. Elhatisari, S. Weinberg, T.A. Lähde   +33 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Recent progress in Hamiltonian light-front QCD [PDF]

, 2008
Hamiltonian light-front quantum field theory constitutes a framework for the non-perturbative solution of invariant masses and correlated parton amplitudes of self-bound systems. By choosing light-front gauge and adopting a basis function representation,
C. Yang, E. G. Ng, H. Honkanen, J. P. Vary, J. P. Vary, Jun Li, P. Maris, P. Sternberg, S. J. Brodsky   +8 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source